Cytokines induce the development of functionally heterogeneous T helper cell subsets (Q41732572)

8 October 2017

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title

Cytokines induce the development of functionally heterogeneous T helper cell subsets (English)

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8 October 2017

1

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8 October 2017

language of work or name

English

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publication date

1 March 1998

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8 October 2017

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8 October 2017

volume

8

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8 October 2017

issue

3

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8 October 2017

page(s)

275-283

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Functional diversity of helper T lymphocytes

8 October 2017

cites work

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Distinct types of lung disease caused by functional subsets of antiviral T cells

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A newly defined interleukin-1?

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Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice

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Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma

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7 January 2021

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A role for CD4 in peripheral T cell differentiation

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7 January 2021

In vivo role of interleukin 4 in T cell tolerance induced by aqueous protein antigen

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IRAK: a kinase associated with the interleukin-1 receptor

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

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Impaired NK1+ T cell development and early IL-4 production in CD1-deficient mice.

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Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches

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Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

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Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells

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7 January 2021

The injection of deaggregated gamma globulins in adult mice induces antigen-specific unresponsiveness of T helper type 1 but not type 2 lymphocytes

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7 January 2021

Differential regulation of murine T lymphocyte subsets

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7 January 2021

Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential

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7 January 2021

Impaired Th2 subset development in the absence of CD4.

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7 January 2021

Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts

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7 January 2021

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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7 January 2021

Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development

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7 January 2021

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

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7 January 2021

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

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7 January 2021

An interleukin-4-induced transcription factor: IL-4 Stat

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7 January 2021

Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system

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7 January 2021

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

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7 January 2021

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

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7 January 2021

Resistance to Leishmania major induced by tolerance to a single antigen

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7 January 2021

The relationship of IL-4- and IFNγ-producing T cells studied by lineage ablation of IL-4-producing cells

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7 January 2021

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

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7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

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7 January 2021

Mechanism of suppression of cell-mediated immunity by measles virus

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7 January 2021

Th1 and Th2 subsets: paradigms lost?

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7 January 2021

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

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7 January 2021

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

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7 January 2021

T-cell subset-specific expression of the IL-4 gene is regulated by a silencer element and STAT6.

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7 January 2021

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

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7 January 2021

Generation and analysis of interleukin-4 deficient mice

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7 January 2021

Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

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7 January 2021

IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice

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7 January 2021

Cytokine transcriptional events during helper T cell subset differentiation

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7 January 2021

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

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7 January 2021

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

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7 January 2021

Role of interleukin 1 in the activation of T lymphocytes

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7 January 2021

Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function

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7 January 2021

IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses

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7 January 2021

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

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7 January 2021

CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4

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7 January 2021

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7 January 2021

Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse

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7 January 2021

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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7 January 2021

B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation

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7 January 2021

T-cell subsets in autoimmunity

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7 January 2021

Cloning of a new cytokine that induces IFN-gamma production by T cells

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7 January 2021

T Helper 2 (Th2) T Cells Induce Acute Pancreatitis and Diabetes in Immune-compromised Nonobese Diabetic (NOD) Mice

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7 January 2021

Cytokine regulation of T-cell function: potential for therapeutic intervention

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7 January 2021

OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset

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7 January 2021

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

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7 January 2021

Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells

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7 January 2021

Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells

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7 January 2021

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

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7 January 2021

Selective expression of an interleukin-12 receptor component by human T helper 1 cells

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7 January 2021

Lymphokine production by human T cells in disease states

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7 January 2021

Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene

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7 January 2021

Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor

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7 January 2021

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism

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7 January 2021

Uptake of microparticle-adsorbed protein antigen by bone marrow-derived dendritic cells results in up-regulation of interleukin-1 alpha and interleukin-12 p40/p35 and triggers prolonged, efficient antigen presentation.

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7 January 2021

T helper type 1 development of naive CD4+ T cells requires the coordinate action of interleukin-12 and interferon-gamma and is inhibited by transforming growth factor-beta

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7 January 2021

A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity

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7 January 2021

Acquisition of lymphokine-producing phenotype by CD4+ T cells

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7 January 2021

Regulation of immunity to parasites by T cells and T cell-derived cytokines

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7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

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7 January 2021

Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells

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7 January 2021

The dendritic cell system and its role in immunogenicity

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7 January 2021

Developmental commitment to the Th2 lineage by extinction of IL-12 signaling

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7 January 2021

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

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7 January 2021

Essential role of Stat6 in IL-4 signalling

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7 January 2021

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

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7 January 2021

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

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7 January 2021

Oral tolerance for the treatment of autoimmune diseases

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7 January 2021

Role of NK1.1+ T cells in a TH2 response and in immunoglobulin E production

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7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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7 January 2021

10.1016/S1074-7613(00)80533-6

Identifiers

DOI

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8 October 2017

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