ezetimibe (Q417997)

Ezetimibe (English)

3 October 2016

C₂₄H₂₁F₂NO₃

1 reference

Ezetimibe (English)

20 November 2016

C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O

1 reference

Ezetimibe (English)

20 November 2016

C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O

1 reference

https://www.whocc.no/atc_ddd_index/?code=C10AX09

Ezetimibe (English)

20 November 2016

10 milligram

route of administration

oral administration

1 reference

reference URL

1 reference

14 February 2018

World Health Organisation international non-proprietary name

ezetimibe (English)

1 reference

ezetimibe (English)

medical condition treated

3 October 2016

familial hypercholesterolemia

1 reference

familial hypercholesterolemia

13 December 2016

start time

24 October 2002

approved by

Food and Drug Administration

applies to jurisdiction

United States of America

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/EOR26LQQ24

2 November 2018

reference URL

https://www.drugs.com/dosage/ezetimibe.html

lipedema

1 reference

Drug Indications Extracted from FAERS

2 October 2018

rare dyslipidemia

1 reference

Drug Indications Extracted from FAERS

significant drug interaction

2 October 2018

fenofibrate

side effect

cholelithiasis

1 reference

sourcing circumstances

established

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

NPC1 like intracellular cholesterol transporter 1

subject has role

antagonist

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6816

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

17 August 2016

route of administration

oral administration

0 references

legal status (medicine)

boxed warning

1 reference

reference URL

Australian pregnancy category C

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

pregnancy category

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category C

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category C

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Ezetimibe

last update

18 February 2018

subject has role

anticholesteremic agents

1 reference

Medical Subject Headings

MeSH descriptor ID

D000069438

InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1

15 March 2018

lipid regulating agents

0 references

Commons category

Ezetimibe

0 references

Identifiers

InChI

1 reference

Ezetimibe (English)

20 November 2016

2 references

Ezetimibe (English)

20 November 2016

ChEBI release 2020-09-01

CAS Registry Number

163222-33-1

2 references

ezetimibe (English)

20 November 2016

https://commonchemistry.cas.org/detail?cas_rn=163222-33-1

10 April 2021

1 reference

ezetimibe (English)

20 November 2016

2 references

Ezetimibe (English)

20 November 2016

Reaxys registry number

7981967

1 reference

ezetimibe (English)

3 October 2016

mapping relation type

2 references

EZETIMIBE (English)

20 November 2016

International Chemical Identifier

InChI

InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1

1 reference

EZETIMIBE (English)

20 November 2016

2 references

inferred from InChIKey

splash10-00di-0090000000-2095f1a903775ffc154f

1 reference

0 references

HSDB ID

7737

1 reference

Hazardous Substances Data Bank

28 October 2019

Ezetimibe (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.207.996

27 December 2018

ECHA Substance Infocard ID

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (English)

quotation

CAS no.: 163222-33-1 (English)

100.207.996

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.207.996

27 December 2018

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (English)

quotation

CAS no.: 163222-33-1 (English)

1 reference

World Health Organisation international non-proprietary name numeric ID

Ezetimibe (English)

publication date

17 November 2015

8010

0 references

Guide to Pharmacology Ligand ID

6816

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6816

ezetimibe (English)

20 November 2016

Ezetimibe

0 references

0 references

0 references

1 reference

ezetimibe (English)

20 November 2016

1 reference

Human Metabolome Database ID

HMDB0015108

2 references

based on heuristic

inferred from InChIKey

2 references

ezetimibe (English)

20 November 2016

MedlinePlus drug identifier

a603015

0 references

PatientsLikeMe treatment ID

0 references

1 reference

ezetimibe (English)

20 November 2016

0 references

1 reference

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

ezetimibe (English)

3 October 2016

0 references

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

UK Parliament thesaurus ID

529338

subject named as

Ezetimibe

0 references

UMLS CUI

C1142985

1 reference