Translational resistance of late alphavirus mRNA to eIF2alpha phosphorylation: a strategy to overcome the antiviral effect of protein kinase PKR. (Q41866567)

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scientific article published on January 2006

Language	Label	Description	Also known as
English	Translational resistance of late alphavirus mRNA to eIF2alpha phosphorylation: a strategy to overcome the antiviral effect of protein kinase PKR.	scientific article published on January 2006

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Translational resistance of late alphavirus mRNA to eIF2alpha phosphorylation: a strategy to overcome the antiviral effect of protein kinase PKR. (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

phosphorylation

1 reference

based on heuristic

inferred from title

object named as

Miguel Angel Sanz

2

0 references

object named as

Luis Carrasco

5

0 references

author name string

Iván Ventoso

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Susana Molina

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Juan José Berlanga

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Mariano Esteban

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

publication date

1 January 2006

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Genes & Development

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

20

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

87-100

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Novel characteristics of the biological properties of the yeast Saccharomyces cerevisiae eukaryotic initiation factor 2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356103

5 June 2018

PKR-dependent and -independent mechanisms are involved in translational shutoff during Sindbis virus infection.

1 reference

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

1 reference

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Defective translational control facilitates vesicular stomatitis virus oncolysis

1 reference

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5 June 2018

Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356103

5 June 2018

Characterization of mammalian eIF2A and identification of the yeast homolog

1 reference

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Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.

1 reference

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Gene-specific regulation by general translation factors

1 reference

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Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation

1 reference

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5 June 2018

Molecular mechanisms of translation initiation in eukaryotes

1 reference

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

1 reference

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Phosphorylation status of the parvovirus minute virus of mice particle: mapping and biological relevance of the major phosphorylation sites

1 reference

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5 June 2018

Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B.

1 reference

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The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.

1 reference

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Initiation of protein synthesis from the A site of the ribosome

1 reference

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Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

1 reference

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

1 reference

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Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication.

1 reference

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5 June 2018

PKR; a sentinel kinase for cellular stress

1 reference

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Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor

1 reference

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Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

1 reference

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5 June 2018

Eukaryotic initiation factor eIF2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356103

5 June 2018

Primer extension analysis of eukaryotic ribosome-mRNA complexes

1 reference

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How cells respond to interferons

1 reference

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RNA binding and modulation of PKR activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356103

5 June 2018

Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons

1 reference

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Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation

1 reference

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5 June 2018

Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2alpha. Role of the alpha- and delta-subunits of eiF2b

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356103

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Use of vertical slab isoelectric focusing and immunoblotting to evaluate steady-state phosphorylation of eIF2 alpha in cultured cells

1 reference

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The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

1 reference

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The eIF-2alpha kinases and the control of protein synthesis

1 reference

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Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2

1 reference

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Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

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Translation of Sindbis virus mRNA: analysis of sequences downstream of the initiating AUG codon that enhance translation.

1 reference

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Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells

1 reference

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Recombinant vaccinia virus K3L gene product prevents activation of double-stranded RNA-dependent, initiation factor 2 alpha-specific protein kinase

1 reference

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The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms

1 reference

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The alphaviruses: gene expression, replication, and evolution

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Translation of Sindbis virus mRNA: effects of sequences downstream of the initiating codon

1 reference

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1 reference

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1 reference

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1 reference

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Promoter for Sindbis virus RNA-dependent subgenomic RNA transcription

1 reference

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Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes

1 reference

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Translational control in mammalian cells

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Analysis of 40 S and 80 S complexes with mRNA as measured by sucrose density gradients and primer extension inhibition

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Eukaryotic initiation complex formation. Evidence for two distinct pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16391235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16391235

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based on heuristic

inferred from PubMed ID database lookup

Mechanism of interferon action. Activation of the human P1/eIF-2 alpha protein kinase by individual reovirus s-class mRNAs: s1 mRNA is a potent activator relative to s4 mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/16391235

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Double-stranded RNA-dependent protein kinase (PKR) is regulated by reovirus structural proteins

1 reference

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based on heuristic

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Identifiers

10.1101/GAD.357006

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

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