Protective effect of the Y220C mutant p53 against steatosis: good news? (Q42244880)

19 October 2017

title

Protective effect of the Y220C mutant p53 against steatosis: good news? (English)

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19 October 2017

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Manuele Gori

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Barbara Barbaro

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Barbara Barbaro

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Mario Arciello

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Mario Arciello

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Roberta Maggio

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Roberta Maggio

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author name string

Carmela Viscomi

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19 October 2017

Alessia Longo

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19 October 2017

Clara Balsano

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19 October 2017

publication date

1 September 2014

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Journal of Cellular Physiology

19 October 2017

published in

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19 October 2017

volume

229

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19 October 2017

issue

9

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19 October 2017

page(s)

1182-1192

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Nonalcoholic fatty liver disease

19 October 2017

cites work

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ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

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Some p53-binding proteins that can function as arbiters of life and death.

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Hepatic triglyceride synthesis and nonalcoholic fatty liver disease

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Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease

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p53, a novel regulator of lipid metabolism pathways.

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Regulation of lipid metabolism by p53 - fighting two villains with one sword.

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A human hepatocellular in vitro model to investigate steatosis.

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Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

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Mechanisms of disease progression in nonalcoholic fatty liver disease

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GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation

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The complexity of p53 stabilization and activation

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Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis

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The role of SIRT1 in tumorigenesis

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Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome

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Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis.

21 January 2018

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Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

21 January 2018

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SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism

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Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.

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Primary hepatocellular carcinoma and metabolic syndrome: An update

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Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes

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Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

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Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

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Liver steatosis in Polish children assessed by medicolegal autopsies

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Telomere dysfunction induces metabolic and mitochondrial compromise.

21 January 2018

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PGC-1α, a key modulator of p53, promotes cell survival upon metabolic stress

21 January 2018

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Hepatic gene expression in histologically progressive nonalcoholic steatohepatitis

21 January 2018

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Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection

21 January 2018

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p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice.

21 January 2018

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

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Steatosis as a risk factor in liver surgery

21 January 2018

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Blinded by the Light: The Growing Complexity of p53

21 January 2018

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p53 Activation in Adipocytes of Obese Mice

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Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress

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21 January 2018

Identifiers

DOI

10.1002/JCP.24550

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19 October 2017

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