Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms. (Q42256131)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16449526%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms (English)

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16 January 2020

4

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16 January 2020

6

Iannis Aifantis

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16 January 2020

author name string

Erica J Reschly

1

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16 January 2020

Christina Spaulding

2

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16 January 2020

Tomas Vilimas

3

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16 January 2020

Rachel L Brumbaugh

5

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16 January 2020

Warren S Pear

7

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16 January 2020

Barbara L Kee

8

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16 January 2020

language of work or name

English

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publication date

31 January 2006

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16 January 2020

number of pages

7

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based on heuristic

inferred from page(s)

published in

Blood

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16 January 2020

volume

107

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16 January 2020

issue

10

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16 January 2020

page(s)

4115-4121

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Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice

16 January 2020

cites work

1 reference

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Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma

26 October 2017

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Activating Notch1 mutations in mouse models of T-ALL.

26 October 2017

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Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

26 October 2017

1 reference

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Regulation of lymphoid development, differentiation, and function by the Notch pathway.

26 October 2017

1 reference

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The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival

26 October 2017

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A wide role for NOTCH1 signaling in acute leukemia

26 October 2017

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Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats

26 October 2017

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

26 October 2017

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Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A

26 October 2017

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TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.

26 October 2017

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p53 regulates thymic Notch1 activation

26 October 2017

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E2A proteins enforce a proliferation checkpoint in developing thymocytes

26 October 2017

1 reference

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Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma

26 October 2017

1 reference

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Notch-regulated ankyrin-repeat protein inhibits Notch1 signaling: multiple Notch1 signaling pathways involved in T cell development

26 October 2017

1 reference

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Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex

26 October 2017

1 reference

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Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient mice

26 October 2017

1 reference

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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

26 October 2017

1 reference

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Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations

26 October 2017

1 reference

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Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1.

26 October 2017

1 reference

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Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells

26 October 2017

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26 October 2017

The Hallmarks of Cancer

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A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex

26 October 2017

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The SCL gene: from case report to critical hematopoietic regulator.

26 October 2017

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Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.

26 October 2017

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The role of E-proteins in B- and T-lymphocyte development

26 October 2017

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Notch inhibition of E47 supports the existence of a novel signaling pathway

26 October 2017

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High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

26 October 2017

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E2A Deficiency Leads to Abnormalities in αβ T-Cell Development and to Rapid Development of T-Cell Lymphomas

26 October 2017

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Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells

26 October 2017

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26 October 2017

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26 October 2017

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

26 October 2017

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Mastermind critically regulates Notch-mediated lymphoid cell fate decisions.

26 October 2017

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Notch1 expression in early lymphopoiesis influences B versus T lineage determination

17 August 2018

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A critical role for the cytoplasmic tail of pTα in T lymphocyte development

17 August 2018

1 reference

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Analysis of T-cell development by using short interfering RNA to knock down protein expression

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16449526

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16449526

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2005-09-3551

1 reference

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16 January 2020

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16 January 2020

PubMed publication ID

16449526

1 reference