Emerging roles of protein disulfide isomerase in cancer. (Q42357758)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28648146%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

review article

2 references

8 February 2021

Emerging roles of protein disulfide isomerase in cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28648146%20AND%20SRC:MED&resulttype=core&format=json

protein disulfide-isomerase

23 March 2020

main subject

1 reference

28 September 2019

1 reference

8 February 2021

Eunyoug Lee

1

1 reference

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23 March 2020

Do Hee Lee

series ordinal

2

1 reference

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23 March 2020

publication date

1 August 2017

4 references

3 April 2019

28 September 2019

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23 March 2020

8 February 2021

4 references

3 April 2019

28 September 2019

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23 March 2020

8 February 2021

50

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23 March 2020

issue

8

1 reference

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23 March 2020

page(s)

401-410

1 reference

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Creative Commons Attribution-NonCommercial 4.0 International

23 March 2020

copyright license

3 references

3 April 2019

28 September 2019

on focus list of Wikimedia project

8 February 2021

ScienceSource

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cites work

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Secretion of protein disulphide isomerase AGR2 confers tumorigenic properties

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The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in Neurodegeneration

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The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein.

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Regulation and Quality Control of Adiponectin Assembly by Endoplasmic Reticulum Chaperone ERp44.

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Novel roles for protein disulphide isomerase in disease states: a double edged sword?

29 May 2018

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Proteostasis and "redoxtasis" in the secretory pathway: Tales of tails from ERp44 and immunoglobulins

29 May 2018

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Protein disulfide-isomerase, a folding catalyst and a redox-regulated chaperone

29 May 2018

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Structures and functions of protein disulfide isomerase family members involved in proteostasis in the endoplasmic reticulum

29 May 2018

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The role of AGR2 and AGR3 in cancer: similar but not identical.

29 May 2018

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Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface

29 May 2018

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A novel prognostic factor for hepatocellular carcinoma: protein disulfide isomerase.

29 May 2018

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Oxidative protein folding: from thiol-disulfide exchange reactions to the redox poise of the endoplasmic reticulum

29 May 2018

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Endoplasmic reticulum stress-activated transcription factor ATF6α requires the disulfide isomerase PDIA5 to modulate chemoresistance

29 May 2018

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The protein disulfide isomerases PDIA4 and PDIA6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma

29 May 2018

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Occurrence of protein disulfide bonds in different domains of life: a comparison of proteins from the Protein Data Bank

29 May 2018

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Protein disulfide isomerase: a promising target for cancer therapy

29 May 2018

1 reference

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Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization

29 May 2018

1 reference

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ERdj5 is the ER reductase that catalyzes the removal of non-native disulfides and correct folding of the LDL receptor

29 May 2018

1 reference

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A pH-regulated quality control cycle for surveillance of secretory protein assembly

29 May 2018

1 reference

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The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarker

29 May 2018

1 reference

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Structure of the Non-Catalytic Domain of the Protein Disulfide Isomerase-Related Protein (PDIR) Reveals Function in Protein Binding

29 May 2018

1 reference

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The human protein disulfide isomerase gene family

29 May 2018

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Dimerization of pro-oncogenic protein Anterior Gradient 2 is required for the interaction with BiP/GRP78

29 May 2018

1 reference

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Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment

29 May 2018

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Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development.

29 May 2018

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Protein disulfide isomerases in neurodegeneration: from disease mechanisms to biomedical applications

29 May 2018

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Protein disulfide isomerase is required for platelet-derived growth factor-induced vascular smooth muscle cell migration, Nox1 NADPH oxidase expression, and RhoGTPase activation.

29 May 2018

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Protein disulfide isomerase regulates endoplasmic reticulum stress and the apoptotic process during prion infection and PrP mutant-induced cytotoxicity

29 May 2018

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Anterior Gradient-3: a novel biomarker for ovarian cancer that mediates cisplatin resistance in xenograft models

29 May 2018

1 reference

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Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility [corrected].

29 May 2018

1 reference

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Proteomic research progress in lymphatic metastases of cancers

29 May 2018

1 reference

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The protein disulfide isomerase family: key players in health and disease

29 May 2018

1 reference

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Role of pro-oncogenic protein disulfide isomerase (PDI) family member anterior gradient 2 (AGR2) in the control of endoplasmic reticulum homeostasis.

29 May 2018

1 reference

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Identification of two portal vein tumor thrombosis associated proteins in hepatocellular carcinoma: protein disulfide-isomerase A6 and apolipoprotein A-I.

29 May 2018

1 reference

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Calsequestrin distribution, structure and function, its role in normal and pathological situations and the effect of thyroid hormones

29 May 2018

1 reference

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Anterior gradient 2: a novel player in tumor cell biology

29 May 2018

1 reference

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Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins

29 May 2018

1 reference

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Endoplasmic reticulum protein 29 (ERp29): An emerging role in cancer

29 May 2018

1 reference

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How proteins form disulfide bonds

29 May 2018

1 reference

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Over-expression of ERp29 attenuates doxorubicin-induced cell apoptosis through up-regulation of Hsp27 in breast cancer cells

29 May 2018

1 reference

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A structural overview of the PDI family of proteins

29 May 2018

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Functional relationship between protein disulfide isomerase family members during the oxidative folding of human secretory proteins

29 May 2018

1 reference

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Discovery of a novel unfolded protein response phenotype of cancer stem/progenitor cells from the bone marrow of breast cancer patients

29 May 2018

1 reference

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Protein quality control in the ER: the recognition of misfolded proteins

29 May 2018

1 reference

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Thiol isomerases negatively regulate the cellular shedding activity of ADAM17.

29 May 2018

1 reference

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Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation

29 May 2018

1 reference

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Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins.

29 May 2018

1 reference

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Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones

29 May 2018

1 reference

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Disulfide formation in the ER and mitochondria: two solutions to a common process.

29 May 2018

1 reference

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Protein disulfide isomerase: a critical evaluation of its function in disulfide bond formation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Insights into MHC Class I Peptide Loading from the Structure of the Tapasin-ERp57 Thiol Oxidoreductase Heterodimer

29 May 2018

1 reference

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ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

The redox activity of ERp57 is not essential for its functions in MHC class I peptide loading

29 May 2018

1 reference

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Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress.

29 May 2018

1 reference

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The human PDI family: versatility packed into a single fold.

29 May 2018

1 reference

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Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications

29 May 2018

1 reference

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Substrate recognition by the protein disulfide isomerases

29 May 2018

1 reference

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Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis

29 May 2018

1 reference

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Nitrosative stress in the ER: a new role for S-nitrosylation in neurodegenerative diseases.

29 May 2018

1 reference

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ERp27, a new non-catalytic endoplasmic reticulum-located human protein disulfide isomerase family member, interacts with ERp57

29 May 2018

1 reference

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Protein disulfide isomerase serves as a molecular chaperone to maintain estrogen receptor alpha structure and function.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Regulation of NAD(P)H oxidase by associated protein disulfide isomerase in vascular smooth muscle cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer

29 May 2018

1 reference

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Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family

29 May 2018

1 reference

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PDILT, a divergent testis-specific protein disulfide isomerase with a non-classical SXXC motif that engages in disulfide-dependent interactions in the endoplasmic reticulum.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Separate roles and different routing of calnexin and ERp57 in endoplasmic reticulum quality control revealed by interactions with asialoglycoprotein receptor chains

29 May 2018

1 reference

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EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Functional characterization of ERp18, a new endoplasmic reticulum-located thioredoxin superfamily member

29 May 2018

1 reference

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Prolyl 4-hydroxylases, the key enzymes of collagen biosynthesis

29 May 2018

1 reference

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Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER.

29 May 2018

1 reference

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Catalytic activity and chaperone function of human protein-disulfide isomerase are required for the efficient refolding of proinsulin

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

The asp-rich region at the carboxyl-terminus of calsequestrin binds to Ca(2+) and interacts with triadin

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Specificity in substrate binding by protein folding catalysts: tyrosine and tryptophan residues are the recognition motifs for the binding of peptides to the pancreas-specific protein disulfide isomerase PDIp

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

The protein disulphide-isomerase family: unravelling a string of folds

29 May 2018

1 reference

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ERp28, a human endoplasmic-reticulum-lumenal protein, is a member of the protein disulfide isomerase family but lacks a CXXC thioredoxin-box motif

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Endo-PDI is required for TNFα-induced angiogenesis.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Human pancreas-specific protein disulfide-isomerase (PDIp) can function as a chaperone independently of its enzymatic activity by forming stable complexes with denatured substrate proteins.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Glycoproteomic analysis of human lung adenocarcinomas using glycoarrays and tandem mass spectrometry: differential expression and glycosylation patterns of vimentin and fetuin A isoforms.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

Protein disulfide isomerase is cleaved by caspase-3 and -7 during apoptosis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5595169

10.5483/BMBREP.2017.50.8.107

17 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28648146%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28648146%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

PubMed publication ID

28648146

1 reference