Engineering small molecule specificity in nearly identical cellular environments. (Q42414857)

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27 December 2019

title

Engineering small molecule specificity in nearly identical cellular environments (English)

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27 December 2019

1

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27 December 2019

author name string

Kryn Stankunas

2

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27 December 2019

Roger Briesewitz

3

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Gerald R Crabtree

4

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27 December 2019

Thomas J Wandless

5

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27 December 2019

language of work or name

English

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publication date

12 March 2007

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Bioorganic & Medicinal Chemistry Letters

27 December 2019

number of pages

3

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based on heuristic

inferred from page(s)

published in

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volume

17

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27 December 2019

issue

10

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27 December 2019

page(s)

2703-2705

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Conditional control of protein function

27 December 2019

cites work

1 reference

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A cell-permeable, activity-based probe for protein and lipid kinases

28 May 2018

1 reference

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An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

28 May 2018

1 reference

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Codominant interference, antieffectors, and multitarget drugs

28 May 2018

1 reference

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Synthesis and biological activity of DNA damaging agents that form decoy binding sites for the estrogen receptor

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1949043

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1949043

The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1949043

Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1949043

Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1949043

Conditional protein alleles using knockin mice and a chemical inducer of dimerization

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1949043

A bifunctional molecule that displays context-dependent cellular activity

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1949043

In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1949043

10.1016/J.BMCL.2007.03.012

16 August 2018

Identifiers

DOI

1 reference

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27 December 2019

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27 December 2019

PubMed publication ID

17383876

1 reference