Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizer (Q42427013)

31 October 2017

Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizer (English)

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adaptive radiation therapy

31 October 2017

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hypoxia

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etanidazole

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ChEBI release 2020-05-28

2

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31 October 2017

J Martin Brown

1

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31 October 2017

Billy W Loo

series ordinal

3

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31 October 2017

language of work or name

English

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publication date

1 October 2010

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International Journal of Radiation Oncology Biology Physics

31 October 2017

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31 October 2017

78

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31 October 2017

2

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31 October 2017

323-327

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Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

31 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Acute skin toxicity following stereotactic body radiation therapy for stage I non-small-cell lung cancer: who's at risk?

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Stereotactic body radiation therapy in centrally and superiorly located stage I or isolated recurrent non-small-cell lung cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Universal survival curve and single fraction equivalent dose: useful tools in understanding potency of ablative radiotherapy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Hypofractionated stereotactic radiotherapy (HypoFXSRT) for stage I non-small cell lung cancer: updated results of 257 patients in a Japanese multi-institutional study

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Stereotactic single-dose radiotherapy (radiosurgery) of early stage nonsmall-cell lung cancer (NSCLC).

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Relationship between pattern of enhancement and local control of brain metastases after radiosurgery

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

The hypoxic cell: a target for selective cancer therapy--eighteenth Bruce F. Cain Memorial Award lecture.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Cells at intermediate oxygen levels can be more important than the "hypoxic fraction" in determining tumor response to fractionated radiotherapy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Radiation and nitroimidazoles in supratentorial high grade gliomas: a second clinical trial

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

The Phenomenon of Reoxygenation and Its Implications for Fractionated Radiotherapy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Misonidazole in fractionated radiotheraphy of a murine mammary carcinoma: Comparison of tumor and normal tissue response

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Radiation and High-Dose Metronidazole in Supratentorial Glioblastomas

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Brachial plexopathy from stereotactic body radiotherapy in early-stage NSCLC: dose-limiting toxicity in apical tumor sites.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Radiation-induced rib fractures after hypofractionated stereotactic body radiation therapy of non-small cell lung cancer: a dose- and volume-response analysis.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

A phase I-B trial of the radiosensitizer: etanidazole (SR-2508) with radiosurgery for the treatment of recurrent previously irradiated primary brain tumors or brain metastases (RTOG Study 95-02).

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

The North American experience with stereotactic body radiation therapy in non-small cell lung cancer

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

RTOG #89-06: a phase I study to evaluate intraoperative radiation therapy and the hypoxic cell sensitizer etanidazole in locally advanced malignancies.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Clinical trials of radiosensitizers: What should we expect?

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939040

Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation

16 August 2018

1 reference

12 December 2020

Optimum fractionation of the C3H mouse mammary carcinoma using x-rays, the hypoxic-cell radiosensitizer Ro-07-0582, or fast neutrons

1 reference

12 December 2020

Tumor response to radiotherapy regulated by endothelial cell apoptosis

1 reference

12 December 2020

Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma

1 reference

12 December 2020

High-dose, single-fraction image-guided intensity-modulated radiotherapy for metastatic spinal lesions

1 reference

12 December 2020

Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors

1 reference

12 December 2020

Dose-response in stereotactic irradiation of lung tumors

1 reference

12 December 2020

Interaction of misonidazole and oxygen in the radiosensitization of mammalian cells

1 reference

12 December 2020

Stereotactic body radiation therapy for early-stage non-small-cell lung carcinoma: four-year results of a prospective phase II study

1 reference

12 December 2020

Stereotactic radiotherapy for unresectable adenocarcinoma of the pancreas

1 reference

12 December 2020

Modification of Hypoxia-Induced Radioresistance in Tumors by the Use of Oxygen and Sensitizers

1 reference

12 December 2020

Efficacy of novel hypoxic cell sensitiser doranidazole in the treatment of locally advanced pancreatic cancer: long-term results of a placebo-controlled randomised study

1 reference

12 December 2020

Observation of a dose-control relationship for lung and liver tumors after stereotactic body radiation therapy

1 reference

12 December 2020

Tumor oxygenation and reoxygenation during radiation therapy: their importance in predicting tumor response

1 reference

12 December 2020

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix

1 reference

12 December 2020

10.1016/J.IJROBP.2010.04.070

Identifiers

DOI

1 reference

31 October 2017

1 reference

31 October 2017

PubMed publication ID

20832663

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