Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes (Q42460893)

1 November 2017

title

Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes (English)

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3

M Orho-Melander

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6

L Groop

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D Tripathy

1

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K F Eriksson

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2

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J Fredriksson

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4

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G Ahlqvist

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5

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publication date

28 April 2004

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volume

47

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issue

5

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page(s)

782-793

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Insulin secretion and insulin sensitivity in diabetic subgroups: studies in the prediabetic and diabetic state

1 November 2017

cites work

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Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians

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Normal hepatic insulin sensitivity in lean, mild noninsulin-dependent diabetic patients

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Relationship between hepatic glucose production and fasting plasma glucose concentration in patients with NIDDM.

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Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells

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Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese

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Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

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Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels

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Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

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Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom

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Relationship between skeletal muscle insulin resistance, insulin-mediated glucose disposal, and insulin binding. Effects of obesity and body fat topography

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Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

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Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

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Fatty acids in the portal vein of the rat regulate hepatic insulin clearance

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12 December 2020

Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose

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12 December 2020

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12 December 2020

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Adipose tissue as a buffer for daily lipid flux

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10.1007/S00125-004-1393-8

Identifiers

DOI

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1 November 2017

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