F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling (Q42487964)

1 November 2017

title

F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling (English)

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1 November 2017

7

Aebersold R

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Wange RL

1

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Isakov N

2

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Burke TR Jr

3

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Otaka A

4

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Roller PP

5

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Watts JD

6

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Samelson LE

8

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language of work or name

English

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publication date

1 January 1995

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Journal of Biological Chemistry

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published in

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volume

270

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1 November 2017

issue

2

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1 November 2017

page(s)

944-948

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Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon.

1 November 2017

cites work

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Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor zeta chain

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Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain

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Antigen receptor tail clue.

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The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein

21 January 2018

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Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

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Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

21 January 2018

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Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

21 January 2018

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CD3 stimulation causes phosphorylation of phospholipase C-gamma 1 on serine and tyrosine residues in a human T-cell line

21 January 2018

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Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.

21 January 2018

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Signal transduction by lymphocyte antigen receptors

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Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

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SH2 domains recognize specific phosphopeptide sequences

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21 January 2018

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Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5

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Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide

21 January 2018

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Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation

21 January 2018

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Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.

21 January 2018

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Expression, purification, and characterization of the functional dimeric cytoplasmic domain of human erythrocyte band 3 in Escherichia coli

21 January 2018

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p56lck interacts via its src homology 2 domain with the ZAP-70 kinase

21 January 2018

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p56lck-independent activation and tyrosine phosphorylation of p72syk by T-cell antigen receptor/CD3 stimulation

21 January 2018

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New intracellular targets for therapeutic drug design

21 January 2018

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The T cell receptor associated CD3-epsilon protein is phosphorylated upon T cell activation in the two tyrosine residues of a conserved signal transduction motif

21 January 2018

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Characterization of the T cell antigen receptor--p60fyn protein tyrosine kinase association by chemical cross-linking

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.270.2.944

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1 November 2017

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