Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression (Q42483046)

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title

Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression (English)

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Erika Abel

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author name string

Inok Surh

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Joyce Rundhaug

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Amy Pavone

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Carol Mikulec

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Susan M Fischer

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publication date

25 January 2011

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published in

Molecular Carcinogenesis

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volume

50

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issue

6

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page(s)

458-468

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Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

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cites work

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The role of COX-2 in oral cancer development, and chemoprevention/ treatment of oral cancer by selective COX-2 inhibitors

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Cyclooxygenase 2: a molecular target for cancer prevention and treatment

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Immunohistochemical expression of cyclooxygenase-2 in skin cancers

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Localization of prostaglandin H synthase isoenzymes in murine epidermal tumors: suppression of skin tumor promotion by inhibition of prostaglandin H synthase-2.

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Reduction of UV-induced skin tumors in hairless mice by selective COX-2 inhibition

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Enhancement of colon carcinogenesis by prostaglandin E2 administration

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Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis

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The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent.

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Reactive oxygen in the tumor promotion stage of skin carcinogenesis.

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Cyclooxygenase-2 and its role in colorectal cancer development

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Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade

21 January 2018

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Immunolocalization of low-affinity prostaglandin E receptors, EP and EP, in adult human epidermis

21 January 2018

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Differential expression of E prostanoid receptors in murine and human non-melanoma skin cancer

21 January 2018

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The expression pattern of prostaglandin E synthase and EP receptor isoforms in normal mouse skin and preinvasive skin neoplasms

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Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

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Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development.

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Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development

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Importance of the EP(1) receptor in cutaneous UVB-induced inflammation and tumor development

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Suppression of azoxymethane-induced colon cancer development in rats by a prostaglandin E receptor EP1-selective antagonist.

21 January 2018

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A prostaglandin E2 receptor subtype EP1-selective antagonist, ONO-8711, suppresses 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.

21 January 2018

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Chemopreventive effects of ONO-8711, a selective prostaglandin E receptor EP(1) antagonist, on breast cancer development

21 January 2018

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Prostaglandin E receptor subtype EP(1) deficiency inhibits colon cancer development.

21 January 2018

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The growth of malignant keratinocytes depends on signaling through the PGE(2) receptor EP1

21 January 2018

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Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner.

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Prostaglandin E(2) (PGE(2)) induces the c-fos and c-jun expressions via the EP(1) subtype of PGE receptor in mouse osteoblastic MC3T3-E1 cells

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Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt.

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Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis

21 January 2018

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Protein kinase C family: on the crossroads of cell signaling in skin and tumor epithelium

21 January 2018

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Protein kinase Cepsilon and development of squamous cell carcinoma, the nonmelanoma human skin cancer

21 January 2018

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Prostaglandin E2 (PGE2) autoamplifies its production through EP1 subtype of PGE receptor in mouse osteoblastic MC3T3-E1 cells

21 January 2018

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Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: a novel mechanism of lymphangiogenesis in lung adenocarcinoma

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Structure-activity relationships for epidermal ornithine decarboxylase induction and skin tumor promotion by anthrones.

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Identifiers

DOI

10.1002/MC.20730

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1 November 2017

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