The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells. (Q42593798)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19122654%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells (English)

1 reference

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19 January 2020

1 reference

1

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19 January 2020

author name string

Jan Schulze-Luehrman

2

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19 January 2020

Matthew S Hayden

3

1 reference

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19 January 2020

Naoko Hashimoto

4

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19 January 2020

Wataru Ogawa

5

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19 January 2020

Masato Kasuga

6

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19 January 2020

Sankar Ghosh

7

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19 January 2020

language of work or name

English

0 references

publication date

4 January 2009

1 reference

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19 January 2020

1 reference

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19 January 2020

volume

10

1 reference

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19 January 2020

issue

2

1 reference

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19 January 2020

page(s)

158-166

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Critical roles of the PI3K/Akt signaling pathway in T cell development

19 January 2020

cites work

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Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.

28 May 2018

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Antigen-receptor signaling to nuclear factor kappa B.

28 May 2018

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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

28 May 2018

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Role of the PH domain in regulating in vitro autophosphorylation events required for reconstitution of PDK1 catalytic activity

28 May 2018

1 reference

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Deciphering the pathway from the TCR to NF-kappaB

28 May 2018

1 reference

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Phosphorylation of CARMA1 plays a critical role in T Cell receptor-mediated NF-kappaB activation

28 May 2018

1 reference

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Phosphorylation of the CARMA1 linker controls NF-kappaB activation

28 May 2018

1 reference

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MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10

28 May 2018

1 reference

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PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation

28 May 2018

1 reference

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Molecular genetics of T cell development

28 May 2018

1 reference

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Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation

28 May 2018

1 reference

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Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways

28 May 2018

1 reference

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PDK1, the master regulator of AGC kinase signal transduction

28 May 2018

1 reference

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CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1

28 May 2018

1 reference

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Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions

28 May 2018

1 reference

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Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation

28 May 2018

1 reference

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It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation.

28 May 2018

1 reference

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Essential role of PDK1 in regulating cell size and development in mice

28 May 2018

1 reference

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T-cell regulation by CD28 and CTLA-4.

28 May 2018

1 reference

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Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

28 May 2018

1 reference

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

28 May 2018

1 reference

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Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

28 May 2018

1 reference

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AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

28 May 2018

1 reference

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Differential T cell costimulatory requirements in CD28-deficient mice

28 May 2018

1 reference

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The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

28 May 2018

1 reference

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The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development

16 August 2018

1 reference

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T-cell-antigen recognition and the immunological synapse

16 August 2018

1 reference

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A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

16 August 2018

1 reference

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Absence of B7-dependent responses in CD28-deficient mice

16 August 2018

1 reference

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Modeling and analysis on the internal impact of a Stewart platform utilized for spacecraft docking

3 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.1687

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.1687

Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19122654

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.1687

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19122654%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19122654%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

19122654

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19122654%20AND%20SRC:MED&resulttype=core&format=json