Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity (Q42733799)

6 November 2017

Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity (English)

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6 November 2017

Shamina M Rangwala

1

1 reference

6 November 2017

Xiaomei Wang

2

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6 November 2017

Jennifer A Calvo

3

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6 November 2017

Loren Lindsley

4

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6 November 2017

Yunyu Zhang

5

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6 November 2017

Galina Deyneko

6

1 reference

6 November 2017

Valerie Beaulieu

7

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6 November 2017

Jiaping Gao

8

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6 November 2017

Gordon Turner

9

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6 November 2017

Judit Markovits

10

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6 November 2017

language of work or name

English

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publication date

23 April 2010

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Journal of Biological Chemistry

6 November 2017

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6 November 2017

285

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6 November 2017

29

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6 November 2017

22619-22629

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describes a project that uses

6 November 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/2903389

based on heuristic

inferred from PubMed Central ID database lookup

cites work

ERRgamma regulates cardiac, gastric, and renal potassium homeostasis

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An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells

27 May 2018

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PPAR{delta} agonism activates fatty acid oxidation via PGC-1{alpha} but does not increase mitochondrial gene expression and function

27 May 2018

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PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

27 May 2018

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Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation

27 May 2018

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Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults

27 May 2018

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RETRACTED: Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype

27 May 2018

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Transcriptional control of energy homeostasis by the estrogen-related receptors

27 May 2018

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Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors

27 May 2018

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Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy

27 May 2018

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The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha

27 May 2018

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Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers

27 May 2018

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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

27 May 2018

1 reference

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Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis

27 May 2018

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Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

27 May 2018

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Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity

27 May 2018

1 reference

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X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation

27 May 2018

1 reference

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Effects of exercise on mitochondrial content and function in aging human skeletal muscle

27 May 2018

1 reference

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Signaling pathways in skeletal muscle remodeling

27 May 2018

1 reference

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Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection.

27 May 2018

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Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise

27 May 2018

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Decline in skeletal muscle mitochondrial function with aging in humans

27 May 2018

1 reference

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Regulation of muscle fiber type and running endurance by PPARdelta

27 May 2018

1 reference

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Regulation of PPARgamma coactivator 1alpha (PGC-1alpha) signaling by an estrogen-related receptor alpha (ERRalpha) ligand

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice

27 May 2018

1 reference

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Down-regulation of hypoxia-inducible factor-2 in PC12 cells by nerve growth factor stimulation

27 May 2018

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DAVID: Database for Annotation, Visualization, and Integrated Discovery

27 May 2018

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Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

27 May 2018

1 reference

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Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

27 May 2018

1 reference

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Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

27 May 2018

1 reference

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Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma

27 May 2018

1 reference

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Invited Review: contractile activity-induced mitochondrial biogenesis in skeletal muscle

27 May 2018

1 reference

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Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake

27 May 2018

1 reference

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A role for the transcriptional coactivator PGC-1alpha in muscle refueling

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesity

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903389

Regular endurance training reduces the exercise induced HIF-1alpha and HIF-2alpha mRNA expression in human skeletal muscle in normoxic conditions

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20418374

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20418374

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.125401

1 reference

6 November 2017

1 reference

6 November 2017

PubMed publication ID

20418374

1 reference