Use and properties of ROCK-specific inhibitor Y-27632. (Q42834896)

8 November 2017

title

Use and properties of ROCK-specific inhibitor Y-27632. (English)

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8 November 2017

Narumiya S

1

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8 November 2017

Ishizaki T

series ordinal

2

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8 November 2017

Uehata M

series ordinal

3

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8 November 2017

language of work or name

English

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publication date

1 January 2000

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8 November 2017

published in

Methods in Enzymology

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8 November 2017

volume

325

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8 November 2017

page(s)

273-284

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The small GTPase Rho: cellular functions and signal transduction

8 November 2017

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p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

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p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

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Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases

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Mildly oxidized low density lipoprotein induces contraction of human endothelial cells through activation of Rho/Rho kinase and inhibition of myosin light chain phosphatase

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The effects of the selective ROCK inhibitor, Y27632, on ET-1-induced hypertrophic response in neonatal rat cardiac myocytes--possible involvement of Rho/ROCK pathway in cardiac muscle cell hypertrophy

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Rho Controls Cortical F-actin Disassembly in Addition to, but Independently of, Secretion in Mast Cells

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7 January 2021

ROCK inhibitor Y-27632 attenuates stellate cell contraction and portal pressure increase induced by endothelin-1

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7 January 2021

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7 January 2021

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The effects of the Rho-kinase inhibitor Y-27632 on arachidonic acid-, GTPgammaS-, and phorbol ester-induced Ca2+-sensitization of smooth muscle

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7 January 2021

Relaxation of contracted rabbit tracheal and human bronchial smooth muscle by Y-27632 through inhibition of Ca2+ sensitization

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7 January 2021

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Identifiers

DOI

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8 November 2017

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