Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants (Q42834906)

8 November 2017

title

Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants (English)

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Santiago Rodriguez de Córdoba

8 November 2017

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reactive oxygen species

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8 November 2017

José Antonio Enríquez

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8 November 2017

Patricio Fernández-Silva

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Patricio Fernández-Silva

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author name string

Raquel Moreno-Loshuertos

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8 November 2017

Rebeca Acín-Pérez

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8 November 2017

Nieves Movilla

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8 November 2017

Acisclo Pérez-Martos

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8 November 2017

M Esther Gallardo

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8 November 2017

language of work or name

English

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publication date

1 October 2006

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8 November 2017

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8 November 2017

volume

38

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issue

11

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8 November 2017

page(s)

1261-1268

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Human mtDNA haplogroups associated with high or reduced spermatozoa motility

8 November 2017

cites work

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Differences of sperm motility in mitochondrial DNA haplogroup U sublineages

21 January 2018

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Mitochondrial DNA polymorphisms associated with longevity in a Finnish population

21 January 2018

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The role of mtDNA background in disease expression: a new primary LHON mutation associated with Western Eurasian haplogroup J.

21 January 2018

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Low penetrance of the 14484 LHON mutation when it arises in a non‐haplogroup J mtDNA background

21 January 2018

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mtDNA variation, climatic adaptation, degenerative diseases, and longevity

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Mitochondrial medicine

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Effects of purifying and adaptive selection on regional variation in human mtDNA.

21 January 2018

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A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice

21 January 2018

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Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss

21 January 2018

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Mitochondrial DNA modifies cognition in interaction with the nuclear genome and age in mice

21 January 2018

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Respiratory function in cybrid cell lines carrying European mtDNA haplogroups: implications for Leber's hereditary optic neuropathy

21 January 2018

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An evolutionary perspective on pathogenic mtDNA mutations: haplogroup associations of clinical disorders

21 January 2018

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An intragenic suppressor in the cytochrome c oxidase I gene of mouse mitochondrial DNA.

21 January 2018

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The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme

21 January 2018

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Respiratory complex III is required to maintain complex I in mammalian mitochondria

21 January 2018

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Maternally transmitted histocompatibility antigen of mice: a hydrophobic peptide of a mitochondrially encoded protein

21 January 2018

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Revisiting the mouse mitochondrial DNA sequence

21 January 2018

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Free radicals in the physiological control of cell function

21 January 2018

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Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress.

21 January 2018

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Superoxide-induced massive apoptosis in cultured skin fibroblasts harboring the neurogenic ataxia retinitis pigmentosa (NARP) mutation in the ATPase-6 gene of the mitochondrial DNA.

21 January 2018

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Oxidative stress-related alteration of the copy number of mitochondrial DNA in human leukocytes

21 January 2018

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Modulation of mitochondrial function by hydrogen peroxide

21 January 2018

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Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs

21 January 2018

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Superoxide radical and iron modulate aconitase activity in mammalian cells

21 January 2018

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Maternally inherited aminoglycoside-induced and nonsyndromic deafness is associated with the novel C1494T mutation in the mitochondrial 12S rRNA gene in a large Chinese family

21 January 2018

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Mitochondrial ribosomal RNA mutation associated with both antibiotic–induced and non–syndromic deafness

21 January 2018

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A novel mitochondrial point mutation in a maternal pedigree with sensorineural deafness.

21 January 2018

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The deafness-associated mitochondrial DNA mutation at position 7445, which affects tRNASer(UCN) precursor processing, has long-range effects on NADH dehydrogenase subunit ND6 gene expression.

21 January 2018

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Oxidant signals and oxidative stress

21 January 2018

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Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

21 January 2018

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m.6267G>A: a recurrent mutation in the human mitochondrial DNA that reduces cytochrome c oxidase activity and is associated with tumors

21 January 2018

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Isolation of biogenetically competent mitochondria from mammalian tissues and cultured cells

21 January 2018

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21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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The synthesis of mRNA in isolated mitochondria can be maintained for several hours and is inhibited by high levels of ATP.

21 January 2018

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MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNA(Lys) and premature translation termination

21 January 2018

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Mitochondrial genotype associated with longevity

21 January 2018

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7 January 2021

Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans

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7 January 2021

Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice

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7 January 2021

Selection of a mtDNA sequence variant in hepatocytes of heteroplasmic mice is not due to differences in respiratory chain function or efficiency of replication

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7 January 2021

The free radical theory of aging matures

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7 January 2021

Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress.

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7 January 2021

Use of polarography to detect respiration defects in cell cultures

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7 January 2021

Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader

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7 January 2021

Identifiers

DOI

10.1038/NG1897

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Dimensions Publication ID

8 November 2017

1033903052

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