IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders (Q42858887)

8 November 2017

title

IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders (English)

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8 November 2017

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acute myeloid leukemia

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3

Deng-Feng Zhang

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20946881

2 August 2024

6

Yong-Gang Yao

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20946881

2 August 2024

author name string

Yang Zou

1

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8 November 2017

Yun Zeng

2

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8 November 2017

Shan-Hua Zou

4

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8 November 2017

Yun-Feng Cheng

5

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8 November 2017

language of work or name

English

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publication date

12 October 2010

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full work available at URL

8 November 2017

number of pages

6

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based on heuristic

inferred from page(s)

https://api.elsevier.com/content/article/PII:S0006291X10019005?httpAccept=text/xml

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https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

https://api.elsevier.com/content/article/PII:S0006291X10019005?httpAccept=text/plain

2 August 2024

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https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Biochemical and Biophysical Research Communications

2 August 2024

published in

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8 November 2017

volume

402

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8 November 2017

issue

2

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8 November 2017

page(s)

378-383

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Global cancer statistics, 2002

8 November 2017

cites work

1

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Myeloproliferative neoplasms: contemporary diagnosis using histology and genetics

2 August 2024

2

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Pooled analysis of p53 mutations in hematological malignancies

2 August 2024

3

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

An integrated genomic analysis of human glioblastoma multiforme

2 August 2024

4

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Recurring mutations found by sequencing an acute myeloid leukemia genome

2 August 2024

5

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers

2 August 2024

6

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication

2 August 2024

7

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH mutations in glioma and acute myeloid leukemia

2 August 2024

8

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 and IDH2 mutations in gliomas

2 August 2024

9

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

2 August 2024

10

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms

2 August 2024

11

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors

2 August 2024

12

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value

2 August 2024

13

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms.

2 August 2024

14

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

2 August 2024

15

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia

2 August 2024

16

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

2 August 2024

17

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Analysis of the IDH1 codon 132 mutation in brain tumors

2 August 2024

18

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Recurrent IDH mutations in high-risk myelodysplastic syndrome or acute myeloid leukemia with isolated del(5q).

2 August 2024

20

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias

2 August 2024

21

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation.

2 August 2024

22

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms

2 August 2024

23

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study

2 August 2024

24

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

2 August 2024

25

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor

2 August 2024

26

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

WHO-defined 'myelodysplastic syndrome with isolated del(5q)' in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations

2 August 2024

27

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

2 August 2024

28

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network

2 August 2024

29

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group

2 August 2024

30

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity

2 August 2024

31

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis.

2 August 2024

32

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Prognostic impact of isocitrate dehydrogenase enzyme isoforms 1 and 2 mutations in acute myeloid leukemia: a study by the Acute Leukemia French Association group

2 August 2024

33

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status

2 August 2024

34

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

Mutational analysis of IDH1 codon 132 in non-Hodgkin lymphomas

2 August 2024

35

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

IDH1 R132H mutation is a rare event in myeloproliferative neoplasms as determined by a mutation specific antibody

2 August 2024

36

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.10.038

2 August 2024

Identifiers

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8 November 2017

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