Epidermal growth factor increases the level of the cyclin-dependent kinase (CDK) inhibitor p21/CIP1 (CDK-interacting protein 1) in A431 cells by increasing the half-lives of the p21/CIP1 transcript and the p21/CIP1 protein (Q42992749)

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scientific article published in February 1999

Language	Label	Description	Also known as
English	Epidermal growth factor increases the level of the cyclin-dependent kinase (CDK) inhibitor p21/CIP1 (CDK-interacting protein 1) in A431 cells by increasing the half-lives of the p21/CIP1 transcript and the p21/CIP1 protein	scientific article published in February 1999

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

Epidermal growth factor increases the level of the cyclin-dependent kinase (CDK) inhibitor p21/CIP1 (CDK-interacting protein 1) in A431 cells by increasing the half-lives of the p21/CIP1 transcript and the p21/CIP1 protein (English)

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

author name string

Johannessen LE

1

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

Knardal SL

2

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

Madshus IH

3

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

language of work or name

0 references

publication date

1 February 1999

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Europe PubMed Central

PMC publication ID

12 November 2017

Biochemical Journal

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Europe PubMed Central

PMC publication ID

12 November 2017

337 ( Pt 3)

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

599-606

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

p53-dependent elevation of p21Waf1 expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system

1 reference

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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

1 reference

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High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

1 reference

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Regulating protein degradation by ubiquitination

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New functional activities for the p21 family of CDK inhibitors

1 reference

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Proteasome-dependent regulation of p21WAF1/CIP1 expression

1 reference

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CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein

1 reference

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UVB radiation induces p21Cip1/WAF1 and mediates G1 and S phase checkpoints.

1 reference

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Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

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AU-rich elements: characterization and importance in mRNA degradation

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Induction by EGF and interferon-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei.

1 reference

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p21 is a universal inhibitor of cyclin kinases

1 reference

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WAF1, a potential mediator of p53 tumor suppression

1 reference

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

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Transactivational and DNA binding abilities of endogenous p53 in p53 mutant cell lines

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver.

1 reference

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Induction of WAF1/CIP1 by a p53-independent pathway

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Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

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p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

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Degradation of mRNA in eukaryotes

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Messenger RNA degradation in eukaryotes

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Cell-free activation of a DNA-binding protein by epidermal growth factor

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mRNA stability in mammalian cells

1 reference

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Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition

1 reference

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IL-1 induces expression of WAF1 mRNA in human fibroblasts: mechanisms of accumulation

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Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture

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Specific stimulation of actin gene transcription by epidermal growth factor and cycloheximide

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Epidermal growth factor inhibits the synthesis of the nuclear protein cyclin in A431 human carcinoma cells

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Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells

1 reference

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A p53-independent Pathway for Activation of WAF1/CIP1 Expression Following Oxidative Stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/9895307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of p21 (WAF-1/CIP1) during differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9895307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Number and location of AUUUA motifs: role in regulating transiently expressed RNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/9895307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha: posttranscriptional stabilization of WAF1 mRNA in p53-deficient human leukemic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9895307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocytosed epidermal growth factor (EGF) receptors contribute to the EGF-mediated growth arrest in A431 cells by inducing a sustained increase in p21/CIP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9895307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3370599

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

ResearchGate publication ID

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