In vivo bioassay to detect irinotecan-stabilized DNA/topoisomerase I complexes in rats (Q43137579)

14 November 2017

title

In vivo bioassay to detect irinotecan-stabilized DNA/topoisomerase I complexes in rats (English)

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Bernhard Watzl

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Karlis Briviba

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Karlis Briviba

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author name string

Stephan W Barth

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Nicole Jäger

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Melanie Esselen

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publication date

1 March 2010

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published in

Biotechnology Journal

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volume

5

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issue

3

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page(s)

321-327

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Pharmacology of topoisomerase I inhibitors irinotecan (CPT-11) and topotecan

14 November 2017

cites work

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https://api.crossref.org/works/10.1002%2FBIOT.200900174

Clinical pharmacokinetics of irinotecan and its metabolites: a population analysis

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Topoisomerase I inhibitors: camptothecins and beyond

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Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1- piperidino]carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.200900174

Topoisomerase I and II activity in human breast, cervix, lung and colon cancer

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DNA topoisomerases: structure, function, and mechanism

21 January 2018

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Bioflavonoids as poisons of human topoisomerase II alpha and II beta

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CYP1A1 activation of aminoflavone leads to DNA damage in human tumor cell lines

21 January 2018

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Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIOT.200900174

Evaluation of topotecan and etoposide for non-Hodgkin lymphoma: correlation of topoisomerase-DNA complex formation with clinical response

21 January 2018

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Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

21 January 2018

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A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes.

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Tyrosyl-DNA phosphodiesterase as a target for anticancer therapy

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Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

21 January 2018

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Relationship between development of diarrhea and the concentration of SN-38, an active metabolite of CPT-11, in the intestine and the blood plasma of athymic mice following intraperitoneal administration of CPT-11.

21 January 2018

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Gefitinib increases serum concentrations of oral irinotecan and SN-38 without increasing the biliary concentration of SN-38 in rats.

21 January 2018

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Delphinidin modulates the DNA-damaging properties of topoisomerase II poisons

21 January 2018

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Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

21 January 2018

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Irinotecan causes severe small intestinal damage, as well as colonic damage, in the rat with implanted breast cancer.

21 January 2018

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Food-drug interaction of (-)-epigallocatechin-3-gallate on the pharmacokinetics of irinotecan and the metabolite SN-38.

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VSL#3 probiotic treatment reduces chemotherapy-induced diarrhea and weight loss

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21 January 2018

Identifiers

DOI

10.1002/BIOT.200900174

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14 November 2017

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