In vivo formation of a human beta-globin locus control region core element requires binding sites for multiple factors including GATA-1, NF-E2, erythroid Kruppel-like factor, and Sp1. (Q43576548)

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scientific article published on 13 April 2001

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English	In vivo formation of a human beta-globin locus control region core element requires binding sites for multiple factors including GATA-1, NF-E2, erythroid Kruppel-like factor, and Sp1.	scientific article published on 13 April 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

In vivo formation of a human beta-globin locus control region core element requires binding sites for multiple factors including GATA-1, NF-E2, erythroid Kruppel-like factor, and Sp1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

author name string

Goodwin AJ

1

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Europe PubMed Central

PubMed publication ID

24 November 2017

McInerney JM

2

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Europe PubMed Central

PubMed publication ID

24 November 2017

Glander MA

3

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Europe PubMed Central

PubMed publication ID

24 November 2017

Pomerantz O

4

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Europe PubMed Central

PubMed publication ID

24 November 2017

Lowrey CH

5

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Europe PubMed Central

PubMed publication ID

24 November 2017

language of work or name

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publication date

13 April 2001

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Europe PubMed Central

PubMed publication ID

24 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

24 November 2017

276

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Europe PubMed Central

PubMed publication ID

24 November 2017

29

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Europe PubMed Central

PubMed publication ID

24 November 2017

26883-26892

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Europe PubMed Central

PubMed publication ID

24 November 2017

Activation by locus control regions?

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The "beta-like-globin" gene domain in human erythroid cells

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Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

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Position-independent, high-level expression of the human beta-globin gene in transgenic mice

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Human fetal to adult hemoglobin switching: changes in chromatin structure of the beta-globin gene locus

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Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain

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Conserved elements containing NF-E2 and tandem GATA binding sites are required for erythroid-specific chromatin structure reorganization within the human beta-globin locus control region

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Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights

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The world according to Maf

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Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion

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Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.

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Mechanism of DNase I hypersensitive site formation within the human globin locus control region

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Autonomous, erythroid-specific DNase I hypersensitive site formed by human beta-globin locus control region (LCR) 5' HS 2 in transgenic mice.

1 reference

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Hypersensitive site 4 of the human beta globin locus control region

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NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro

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Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control region

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Structural and functional cross-talk between a distant enhancer and the epsilon-globin gene promoter shows interdependence of the two elements in chromatin

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A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissue-specific transcriptional regulation by EKLF in vitro

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Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein

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Dual promoter activation by the human beta-globin locus control region

1 reference

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21 January 2018

Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells

1 reference

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A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

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Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases

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Molecular analysis of the human beta-globin locus activation region

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Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

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Activation of the erythropoietin receptor promoter by transcription factor GATA-1

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Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein

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Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene

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Cis- and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deaminase gene

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An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes

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Analysis of the tissue-specific enhancer at the 3' end of the chicken adult beta-globin gene

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Erythroid Krüppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the beta-globin locus control region

1 reference

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Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene

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Role of chromatin structure in the regulation of transcription by RNA polymerase II.

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Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity

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Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain

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Characterization of a GC-rich Region Containing Sp1 Binding Site(s) as a Constitutive Responsive Element of the α2(I) Collagen Gene in Human Fibroblasts

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Identifiers

10.1074/JBC.M008410200

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

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