Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation (Q43612082)

25 November 2017

title

Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation (English)

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25 November 2017

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Y Kawamura

1

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25 November 2017

A Kikuchi

2

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R Takada

3

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S Takada

4

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S Sudoh

5

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S Shibamoto

6

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K Yanagisawa

7

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H Komano

8

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25 November 2017

language of work or name

English

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publication date

1 May 2001

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25 November 2017

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volume

268

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issue

10

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25 November 2017

page(s)

3036-3041

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Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

25 November 2017

cites work

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

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Presenilins: genes for life and death

21 January 2018

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Amyloid beta-protein and the genetics of Alzheimer's disease

21 January 2018

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Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

21 January 2018

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Direct association of presenilin-1 with beta-catenin

21 January 2018

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The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

21 January 2018

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Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071

21 January 2018

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Presenilin 1 interaction in the brain with a novel member of the Armadillo family

21 January 2018

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Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin

21 January 2018

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Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

21 January 2018

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Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

21 January 2018

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β-catenin is a target for the ubiquitin–proteasome pathway

21 January 2018

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

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Axin directly interacts with plakoglobin and regulates its stability

21 January 2018

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Roles of Axin in the Wnt signalling pathway

21 January 2018

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Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex

21 January 2018

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Cytoskeletal reorganization by soluble Wnt-3a protein signalling

21 January 2018

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Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

21 January 2018

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Analysis of the 5' sequence, genomic structure, and alternative splicing of the presenilin-1 gene (PSEN1) associated with early onset Alzheimer disease

21 January 2018

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Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

21 January 2018

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Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

21 January 2018

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Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

21 January 2018

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Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled

21 January 2018

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Isolation and characterization of mouse dishevelled-3.

21 January 2018

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The role of beta-catenin stability in mutant PS1-associated apoptosis

21 January 2018

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Wnts as retrograde signals for axon and growth cone differentiation.

21 January 2018

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Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling

21 January 2018

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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

21 January 2018

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Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1

21 January 2018

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Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

21 January 2018

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10.1046/J.1432-1327.2001.02197.X

21 January 2018

Identifiers

DOI

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25 November 2017

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