UGT1A16, 1A73, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan. (Q43714693)

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scientific article published on 27 October 2013

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English	UGT1A16, 1A73, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan.	scientific article published on 27 October 2013

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scholarly article

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21 February 2020

UGT1A1*6, 1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24033692%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

colorectal cancer

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metastatic colon cancer

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based on heuristic

inferred from title

18

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21 February 2020

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Masaaki Oka

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21 February 2020

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Shoichi Hazama

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21 February 2020

Hideyuki Mishima

2

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21 February 2020

Ryouichi Tsunedomi

3

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21 February 2020

Yusuke Okuyama

4

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21 February 2020

Takeshi Kato

5

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21 February 2020

Ken-ichi Takahashi

6

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21 February 2020

Hiroshi Nozawa

7

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21 February 2020

Hideaki Ando

8

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21 February 2020

Michiya Kobayashi

9

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21 February 2020

Hiroyoshi Takemoto

10

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21 February 2020

Naoki Nagata

11

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21 February 2020

Shinsuke Kanekiyo

12

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21 February 2020

Yuka Inoue

13

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21 February 2020

Yoshihiko Hamamoto

14

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21 February 2020

Yusuke Fujita

15

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21 February 2020

Yuji Hinoda

16

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21 February 2020

Naoko Okayama

17

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21 February 2020

Jun-ichi Sakamoto

19

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21 February 2020

publication date

27 October 2013

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21 February 2020

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21 February 2020

104

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21 February 2020

12

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21 February 2020

1662-1669

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21 February 2020

Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

1 reference

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21 January 2018

Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

A novel polymorphism in the promoter region of human UGT1A9 gene (UGT1A9*22) and its effects on the transcriptional activity

1 reference

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21 January 2018

Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

Genetic polymorphisms of the UDP-glucuronosyltransferase 1A7 gene and irinotecan toxicity in Japanese cancer patients

1 reference

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21 January 2018

Gilbert's Syndrome and irinotecan toxicity: combination with UDP-glucuronosyltransferase 1A7 variants increases risk

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21 January 2018

Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens.

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21 January 2018

Prospective phase II study of FOLFIRI for mCRC in Japan, including the analysis of UGT1A1 28/6 polymorphisms.

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21 January 2018

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

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21 January 2018

Phase I study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A1*28 polymorphism

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

Purification of genomic DNA from human whole blood by isopropanol-fractionation with concentrated Nal and SDS.

1 reference

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21 January 2018

Is there diversity among UGT1A1 polymorphism in Japan?

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

Haploview: analysis and visualization of LD and haplotype maps

1 reference

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21 January 2018

Genetic testing for UGT1A1*28 and *6 in Japanese patients who receive irinotecan chemotherapy.

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

1 reference

https://api.crossref.org/works/10.1111%2FCAS.12283

21 January 2018

UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy

1 reference

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21 January 2018

Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11

1 reference

https://pubmed.ncbi.nlm.nih.gov/24033692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24033692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24033692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotype-directed, dose-finding study of irinotecan in cancer patients with UGT1A1*28 and/or UGT1A1*6 polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/24033692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24033692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinogenetics: what is the right star?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24033692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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