E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts (Q43823908)

27 November 2017

title

E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts (English)

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27 November 2017

4

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27 November 2017

Eva M Kovacs

1

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27 November 2017

Radiya G Ali

series ordinal

2

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27 November 2017

Ailsa J McCormack

series ordinal

3

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27 November 2017

language of work or name

English

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publication date

13 December 2001

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Journal of Biological Chemistry

27 November 2017

published in

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27 November 2017

volume

277

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27 November 2017

issue

8

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27 November 2017

page(s)

6708-6718

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Morphogenetic roles of classic cadherins

27 November 2017

cites work

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Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein

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Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function

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Mechanism for transition from initial to stable cell-cell adhesion: kinetic analysis of E-cadherin-mediated adhesion using a quantitative adhesion assay

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Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex.

21 January 2018

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Cadherin engagement regulates Rho family GTPases

21 January 2018

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Cell contact-dependent signaling

21 January 2018

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Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines

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Lateral dimerization is required for the homophilic binding activity of C-cadherin

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase

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Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

21 January 2018

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PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

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Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways

21 January 2018

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Synthesis and function of 3-phosphorylated inositol lipids

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21 January 2018

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GTP-dependent segregation of H-ras from lipid rafts is required for biological activity

21 January 2018

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H-Ras activation promotes cytoplasmic accumulation and phosphoinositide 3-OH kinase association of beta-catenin in epidermal keratinocytes.

21 January 2018

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Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

21 January 2018

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21 January 2018

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p120 catenin regulates the actin cytoskeleton via Rho family GTPases

21 January 2018

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Rho GTPases and their effector proteins

21 January 2018

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Directed actin polymerization is the driving force for epithelial cell-cell adhesion

21 January 2018

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The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

21 January 2018

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Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context.

21 January 2018

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Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells

21 January 2018

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The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn

21 January 2018

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Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

21 January 2018

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Localized Rac activation dynamics visualized in living cells

21 January 2018

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Epithelial cell shape: cadherins and small GTPases

21 January 2018

1 reference

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Regulation of cadherin-mediated cell-cell adhesion by the Rho family GTPases.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109640200

21 January 2018

Identifiers

DOI

10.1074/JBC.M109640200

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27 November 2017

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