Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells. (Q54528615)

30 May 2018

title

Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells. (English)

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30 May 2018

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6

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Martin H Groschup

8

object named as

Martin H Groschup

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9

Hermann M Schätzl

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30 May 2018

Sabine Gilch

1

object named as

Sabine Gilch

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30 May 2018

author name string

Franziska Wopfner

2

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30 May 2018

Ingrid Renner-Müller

3

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30 May 2018

Elisabeth Kremmer

4

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Christine Bauer

5

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30 May 2018

Gottfried Brem

7

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language of work or name

English

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publication date

11 March 2003

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30 May 2018

Journal of Biological Chemistry

number of pages

8

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based on heuristic

inferred from page(s)

published in

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volume

278

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issue

20

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page(s)

18524-18531

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https://api.crossref.org/works/10.1074%2FJBC.M210723200

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Prions and the lymphoreticular system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Structural clues to prion replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Interactions between prion protein isoforms: the kiss of death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Complement facilitates early prion pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Vaccine development for Alzheimer's disease: a shot of good news.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Inhibition of interactions and interconversions of prion protein isoforms by peptide fragments from the C-terminal folded domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Molecular specificities of antibodies against ovine and murine recombinant prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Prion-protein-specific aptamer reduces PrPSc formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Postexposure prophylaxis against prion disease with a stimulator of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Mimicking dominant negative inhibition of prion replication through structure-based drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

Immunization delays the onset of prion disease in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210723200

21 January 2018

Identifiers

DOI

10.1074/JBC.M210723200

1 reference

30 May 2018

1 reference

30 May 2018