Macrophage phenotype and bioenergetics are controlled by oxidized phospholipids identified in lean and obese adipose tissue (Q55031285)

6

object named as

Bimal N Desai

0 references

Clint M. Upchurch

2

object named as

Clint M Upchurch

0 references

Michael Schappe

3

object named as

Michael S. Schappe

0 references

author name string

Vlad Serbulea

1

0 references

Clint M. Upchurch

2

0 references

Paxton Voigt

4

0 references

Dory E. DeWeese

5

0 references

Bimal N. Desai

6

0 references

Akshaya K. Meher

7

0 references

Michael S Schappe

3

0 references

Dory E DeWeese

5

0 references

Akshaya K Meher

Proceedings of the National Academy of Sciences of the United States of America

7

0 references

language of work or name

English

0 references

publication date

11 June 2018

0 references

3 July 2018

0 references

published in

0 references

volume

115

0 references

issue

27

0 references

page(s)

201800544

0 references

E6254-E6263

0 references

copyright license

Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

start time

11 June 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans

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Tissue biology perspective on macrophages

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Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study

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Oxidative lipidomics coming of age: advances in analysis of oxidized phospholipids in physiology and pathology

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Oxidized phospholipids protect against lung injury and endothelial barrier dysfunction caused by heat-inactivated Staphylococcus aureus

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Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

2 November 2018

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

2 November 2018

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Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages

2 November 2018

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Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

2 November 2018

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Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

2 November 2018

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The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity

2 November 2018

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Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids

2 November 2018

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Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

2 November 2018

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Obesity alters adipose tissue macrophage iron content and tissue iron distribution.

2 November 2018

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M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

2 November 2018

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Synthesis of epoxyisoprostanes: effects in reducing secretion of pro-inflammatory cytokines IL-6 and IL-12.

2 November 2018

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Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

2 November 2018

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Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood

2 November 2018

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Structural identification and cardiovascular activities of oxidized phospholipids.

2 November 2018

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Protein modification by aldehydophospholipids and its functional consequences

2 November 2018

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A simplified procedure for semi-targeted lipidomic analysis of oxidized phosphatidylcholines induced by UVA irradiation

2 November 2018

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Aberrant accumulation of undifferentiated myeloid cells in the adipose tissue of CCR2-deficient mice delays improvements in insulin sensitivity.

2 November 2018

1 reference

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Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2.

2 November 2018

1 reference

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Isoprostane generation and function

2 November 2018

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Mass spectrometry analysis of oxidized phosphatidylcholine and phosphatidylethanolamine

2 November 2018

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Oxidative damage in multiple sclerosis lesions

2 November 2018

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Oxidative stress accumulates in adipose tissue during aging and inhibits adipogenesis.

2 November 2018

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Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection

2 November 2018

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Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation.

2 November 2018

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Lysophosphatidylcholine is Generated by Spontaneous Deacylation of Oxidized Phospholipids

2 November 2018

1 reference

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Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.

2 November 2018

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Newly identified adipose tissue macrophage populations in obesity with distinct chemokine and chemokine receptor expression.

2 November 2018

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Adipose tissue macrophages: their role in adipose tissue remodeling

2 November 2018

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Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity

2 November 2018

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Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice

2 November 2018

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Macrophages, inflammation, and insulin resistance

2 November 2018

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Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species

2 November 2018

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Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation

2 November 2018

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Generation and biological activities of oxidized phospholipids

2 November 2018

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Role of macrophage tissue infiltration in obesity and insulin resistance.

2 November 2018

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PPAR gamma is highly expressed in F4/80(hi) adipose tissue macrophages and dampens adipose-tissue inflammation

2 November 2018

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Multi-hit inhibition of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142199

Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142199

Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity.

2 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142199

Oxidation-specific epitopes are important targets of innate immunity

2 November 2018

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Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype.

2 November 2018

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Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study

2 November 2018

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

2 November 2018

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Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells

2 November 2018

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Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice

2 November 2018

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Oxidized phospholipid: POVPC binds to platelet-activating-factor receptor on human macrophages. Implications in atherosclerosis

2 November 2018

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Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease

2 November 2018

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The molecular basis for oxidative stress-induced insulin resistance

2 November 2018

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Increased oxidative stress in obesity and its impact on metabolic syndrome

2 November 2018

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Regulation of inflammatory responses by oxidized phospholipids: structure-function relationships

2 November 2018

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Apoptotic cells as sources for biologically active oxidized phospholipids

2 November 2018

1 reference

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Oxidized phospholipids in minimally modified low density lipoprotein induce apoptotic signaling via activation of acid sphingomyelinase in arterial smooth muscle cells

2 November 2018

1 reference

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Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes

2 November 2018

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A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.

2 November 2018

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Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36

2 November 2018

1 reference

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Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-8 synthesis. Formation of these oxidized phospholipids in response to interleukin-1beta

2 November 2018

1 reference

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Effects of high-fat, low-cholesterol diets on hepatic lipid peroxidation and antioxidants in apolipoprotein E-deficient mice.

2 November 2018

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2 November 2018

1 reference

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Structural identification of a novel pro-inflammatory epoxyisoprostane phospholipid in mildly oxidized low density lipoprotein

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142199

Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142199

Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142199

Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142199

Separation of lipid classes by solid phase extraction

2 November 2018

1 reference

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