Two randomized controlled trials of SB742457 in mild-to-moderate Alzheimer's disease. (Q55297754)

30 June 2018

title

Two randomized controlled trials of SB742457 in mild-to-moderate Alzheimer's disease. (English)

1 reference

30 June 2018

author

Carolyn Bolden-Watson

object named as

Carolyn Watson

2

0 references

Orazio Zanetti

object named as

Orazio Zanetti

9

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author name string

Gareth Maher-Edwards

1

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30 June 2018

John Ascher

3

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30 June 2018

Carly Barnett

4

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30 June 2018

Diane Boswell

5

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30 June 2018

John Davies

6

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30 June 2018

Manuel Fernandez

7

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30 June 2018

Alexander Kurz

8

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30 June 2018

Beth Safirstein

10

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30 June 2018

Juan Paul Schronen

11

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30 June 2018

Marina Zvartau-Hind

12

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30 June 2018

Michael Gold

13

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30 June 2018

publication date

7 May 2015

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30 June 2018

Alzheimer's & dementia (New York, N. Y.)

published in

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30 June 2018

volume

1

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30 June 2018

issue

1

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30 June 2018

page(s)

23-36

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30 June 2018

Safety and efficacy of idalopirdine, a 5-HT6 receptor antagonist, in patients with moderate Alzheimer's disease (LADDER): a randomised, double-blind, placebo-controlled phase 2 trial

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3 July 2018

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Double-blind, controlled phase II study of a 5-HT6 receptor antagonist, SB-742457, in Alzheimer's disease

3 July 2018

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Why do so many drugs for Alzheimer's disease fail in development? Time for new methods and new practices?

3 July 2018

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5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease

3 July 2018

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3 July 2018

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Study design factors and patient demographics and their effect on the decline of placebo-treated subjects in randomized clinical trials in Alzheimer's disease.

3 July 2018

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SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.

3 July 2018

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3 July 2018

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5‐HT6 receptor antagonist SB‐271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex

3 July 2018

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Influence of the 5-HT6 receptor on acetylcholine release in the cortex: pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist

3 July 2018

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The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus

3 July 2018

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An inventory to assess activities of daily living for clinical trials in Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

3 July 2018

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Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study

3 July 2018

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The Clinical Dementia Rating (CDR): current version and scoring rules

3 July 2018

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Pathological verification of ischemic score in differentiation of dementias.

3 July 2018

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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

3 July 2018

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Cornell Scale for Depression in Dementia

3 July 2018

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3 July 2018

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Two novel 5-HT6 receptor antagonists ameliorate scopolamine-induced memory deficits in the object recognition and object location tasks in Wistar rats

3 July 2018

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SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled study

12 August 2018

1 reference

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12 August 2018

Dimebon disappointment

1 reference

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Predictors of placebo group decline in the Alzheimer's disease Assessment Scale-cognitive subscale (ADAS-Cog) in 24 week clinical trials of Alzheimer's disease.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5974972

Handling drop-out in longitudinal clinical trials: a comparison of the LOCF and MMRM approaches.

12 August 2018

1 reference

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Cerebrolysin in Alzheimer's disease: a randomized, double-blind, placebo-controlled trial with a neurotrophic agent.

12 August 2018

1 reference

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10.1016/J.TRCI.2015.04.001

12 August 2018

Identifiers

DOI

1 reference

30 June 2018

release_npkgk2tl5ra6ragmnabknhg6pi

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/npkgk2tl5ra6ragmnabknhg6pi

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

5974972

1 reference

30 June 2018

PubMed publication ID

29854923

1 reference

30 June 2018