Gab1 is required for EGF receptor signaling and the transformation by activated ErbB2 (Q58173527)

1

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Keigo Nishida

2

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Yuichi Yoshida

3

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Motoyuki Itoh

4

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Toshio Hirano

Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding.

6

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language of work or name

English

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publication date

March 2003

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published in

Oncogene

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volume

22

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issue

10

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page(s)

1546-1556

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

Essential role of Gab1 for signaling by the c-Met receptor in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021

Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021

Gab-family adapter molecules in signal transduction of cytokine and growth factor receptors, and T and B cell antigen receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021

Signaling--2000 and beyond

1 reference

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7 January 2021

DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206284

7 January 2021