Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252 (Q58438131)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10601311%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252 (English)

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2 November 2019

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5

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2 November 2019

author name string

A Balendran

1

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2 November 2019

R Currie

2

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2 November 2019

C G Armstrong

3

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2 November 2019

J Avruch

4

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2 November 2019

language of work or name

English

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publication date

1 December 1999

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Journal of Biological Chemistry

2 November 2019

number of pages

7

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based on heuristic

inferred from page(s)

published in

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2 November 2019

volume

274

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2 November 2019

issue

52

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2 November 2019

page(s)

37400-37406

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p70 S6 kinase: an enigma with variations

2 November 2019

cites work

1 reference

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

21 January 2018

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The modular phosphorylation and activation of p70s6k.

21 January 2018

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Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies

21 January 2018

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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

21 January 2018

1 reference

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Phosphorylation and activation of p70s6k by PDK1

21 January 2018

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Mechanism of activation and function of protein kinase B.

21 January 2018

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The extended protein kinase C superfamily

21 January 2018

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Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

21 January 2018

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Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

21 January 2018

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Intracellular signalling: PDK1--a kinase at the hub of things

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

21 January 2018

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

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Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

21 January 2018

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Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

21 January 2018

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Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

21 January 2018

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Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

21 January 2018

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Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase

21 January 2018

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PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

21 January 2018

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Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

21 January 2018

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Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha

21 January 2018

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

21 January 2018

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Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

21 January 2018

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p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complex

21 January 2018

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Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex

21 January 2018

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Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling

21 January 2018

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Kinase phosphorylation: Keeping it all in the family

21 January 2018

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RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

21 January 2018

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Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

21 January 2018

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Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 January 2018

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Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

21 January 2018

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p70s6k function is essential for G1 progression

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.52.37400

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10601311%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference