The Delivery Challenge in Neurodegenerative Disorders: The Nanoparticles Role in Alzheimer's Disease Therapeutics and Diagnostics (Q58548232)

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scientific article published on 17 October 2018

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English	The Delivery Challenge in Neurodegenerative Disorders: The Nanoparticles Role in Alzheimer's Disease Therapeutics and Diagnostics	scientific article published on 17 October 2018

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scholarly article

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Europe PubMed Central

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6321229

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30336640%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 April 2020

title

The Delivery Challenge in Neurodegenerative Disorders: The Nanoparticles Role in Alzheimer's Disease Therapeutics and Diagnostics (English)

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stated in

Europe PubMed Central

PMC publication ID

6321229

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30336640%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 April 2020

main subject

nanoparticle

1 reference

based on heuristic

inferred from title

neurodegeneration

1 reference

based on heuristic

inferred from title

Alzheimer's disease

1 reference

based on heuristic

inferred from title

author

Cristina de la Torre

series ordinal

1

1 reference

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Europe PubMed Central

PMC publication ID

6321229

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30336640%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 April 2020

Valentín Ceña

series ordinal

2

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stated in

Europe PubMed Central

PMC publication ID

6321229

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30336640%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 April 2020

author name string

Cristina de la Torre

series ordinal

1

0 references

Valentín Ceña

series ordinal

2

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language of work or name

English

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publication date

17 October 2018

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Europe PubMed Central

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6321229

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29 April 2020

published in

Pharmaceutics

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stated in

Europe PubMed Central

PMC publication ID

6321229

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30336640%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 April 2020

volume

10

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Europe PubMed Central

PMC publication ID

6321229

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29 April 2020

issue

4

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Europe PubMed Central

PMC publication ID

6321229

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29 April 2020

copyright license

Creative Commons Attribution 4.0 International

start time

17 October 2018

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April 2022 Public Data File from Crossref

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cites work

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Dendrimer-mediated siRNA delivery knocks down Beclin 1 and potentiates NMDA-mediated toxicity in rat cortical neurons.

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Carbon nanotube inhibits the formation of β-sheet-rich oligomers of the Alzheimer's amyloid-β(16-22) peptide

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Roles of NG2 glial cells in diseases of the central nervous system

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Phosphorus dendrimers affect Alzheimer's (Aβ1-28) peptide and MAP-Tau protein aggregation.

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Pivotal role of the RanBP9-cofilin pathway in Aβ-induced apoptosis and neurodegeneration

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Dendrimers reduce toxicity of Aβ 1-28 peptide during aggregation and accelerate fibril formation

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Development and evaluation of rivastigmine loaded chitosan nanoparticles for brain targeting

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Pharmacokinetic behavior and efficiency of acetylcholinesterase inhibition in rat brain after intranasal administration of galanthamine hydrobromide loaded flexible liposomes

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A foldamer-dendrimer conjugate neutralizes synaptotoxic β-amyloid oligomers

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Negatively charged gold nanoparticles inhibit Alzheimer's amyloid-β fibrillization, induce fibril dissociation, and mitigate neurotoxicity.

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Indomethacin-loaded lipid-core nanocapsules reduce the damage triggered by Aβ1-42 in Alzheimer's disease models.

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Functionalized carbon nanotubes: biomedical applications

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SPION-enhanced magnetic resonance imaging of Alzheimer's disease plaques in AβPP/PS-1 transgenic mouse brain

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Preparation, characterization, in vivo and biochemical evaluation of brain targeted Piperine solid lipid nanoparticles in an experimentally induced Alzheimer's disease model

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Stable conjugates of peptides with gold nanorods for biomedical applications with reduced effects on cell viability

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Enhanced brain distribution and pharmacodynamics of rivastigmine by liposomes following intranasal administration

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

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https://pubmed.ncbi.nlm.nih.gov/30336640

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based on heuristic

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Molecular mechanisms of dendrite stability

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A carbon nanotube metal semiconductor field effect transistor-based biosensor for detection of amyloid-beta in human serum

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inferred from PubMed ID database lookup

Autophagy is involved in oligodendroglial precursor-mediated clearance of amyloid peptide

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based on heuristic

inferred from PubMed ID database lookup

Drug delivery to the central nervous system by polymeric nanoparticles: what do we know?

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reference URL

https://pubmed.ncbi.nlm.nih.gov/30336640

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of poly(propylene imine) glycodendrimers on beta-amyloid aggregation in vitro and in APP/PS1 transgenic mice, as a model of brain amyloid deposition and Alzheimer's disease

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Dual-functional nanoparticles targeting amyloid plaques in the brains of Alzheimer's disease mice

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based on heuristic

inferred from PubMed ID database lookup

Acetylcholinesterase inhibitors: pharmacology and toxicology

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Antibody-conjugated, dual-modal, near-infrared fluorescent iron oxide nanoparticles for antiamyloidgenic activity and specific detection of amyloid-β fibrils

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Ligand-targeted liposome design: challenges and fundamental considerations.

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Design, synthesis and biological evaluation of multivalent glucosides with high affinity as ligands for brain targeting liposomes

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Phagocytosis of microglia in the central nervous system diseases

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based on heuristic

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Curcumin-loaded nanoparticles potently induce adult neurogenesis and reverse cognitive deficits in Alzheimer's disease model via canonical Wnt/β-catenin pathway

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Engineering theranostic nanovehicles capable of targeting cerebrovascular amyloid deposits.

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based on heuristic

inferred from PubMed ID database lookup

Multifunctional nanoliposomes with curcumin-lipid derivative and brain targeting functionality with potential applications for Alzheimer disease.

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inferred from PubMed ID database lookup

Animal models of Alzheimer disease: historical pitfalls and a path forward

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based on heuristic

inferred from PubMed ID database lookup

Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-walled carbon nanotubes alleviate autophagic/lysosomal defects in primary glia from a mouse model of Alzheimer's disease

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functionalized nanoscale micelles with brain targeting ability and intercellular microenvironment biosensitivity for anti-intracranial infection applications

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aβ Influences Cytoskeletal Signaling Cascades with Consequences to Alzheimer's Disease.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid-β levels in APP/PS1 transgenic mice.

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin-conjugated magnetic nanoparticles for detecting amyloid plaques in Alzheimer's disease mice using magnetic resonance imaging (MRI).

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

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12 December 2020

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inferred from PubMed ID database lookup

RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction

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inferred from PubMed ID database lookup

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

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inferred from PubMed ID database lookup

A sensitive colorimetric strategy for monitoring cerebral β-amyloid peptides in AD based on dual-functionalized gold nanoplasmonic particles.

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Therapeutic approaches of magnetic nanoparticles for the central nervous system

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diversity of astrocyte functions and phenotypes in neural circuits

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complexation as an approach to entrap cationic drugs into cationic nanoparticles administered intranasally for Alzheimer's disease management: preparation and detection in rat brain

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein expression and amyloid accumulation in human aging and Alzheimer's disease: preliminary observations

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel LDL-mimic nanocarrier for the targeted delivery of curcumin into the brain to treat Alzheimer's disease.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes: New Targets for the Treatment of Neurodegenerative Diseases

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual ligand immunoliposomes for drug delivery to the brain.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ins and Outs of Nanoparticle Technology in Neurodegenerative Diseases and Cancer

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanotheranostics: Congo Red/Rutin-MNPs with Enhanced Magnetic Resonance Imaging and H2O2-Responsive Therapy of Alzheimer's Disease in APPswe/PS1dE9 Transgenic Mice

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptides and proteins used to enhance gold nanoparticle delivery to the brain: preclinical approaches

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galantamine-loaded solid-lipid nanoparticles for enhanced brain delivery: preparation, characterization, in vitro and in vivo evaluations

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https://pubmed.ncbi.nlm.nih.gov/30336640

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hunt for brain Aβ oligomers by peripherally circulating multi-functional nanoparticles: Potential therapeutic approach for Alzheimer disease

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanostructured lipid carriers: Promising drug delivery systems for future clinics

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous penetration of gold nanoparticles through the blood brain barrier (BBB).

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative challenge in Alzheimer's disease: state of knowledge and future needs.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial Cells - The Key Elements of Alzheimer´s Disease

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https://pubmed.ncbi.nlm.nih.gov/30336640

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Cellular Phase of Alzheimer's Disease

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitigating effect of chrysin loaded solid lipid nanoparticles against Amyloid β25-35 induced oxidative stress in rat hippocampal region: An efficient formulation approach for Alzheimer's disease

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranasal delivery of nanoparticle encapsulated tarenflurbil: A potential brain targeting strategy for Alzheimer's disease

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of PEGylated Immunoliposomes to Deliver Dopamine Across the Blood-Brain Barrier in a Rat Model of Parkinson's Disease.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/30336640

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30336640

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic Strategies for Alzheimer's and Parkinson's Diseases by Means of Drug Delivery Systems

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward sensitive immuno-based detection of tau protein by surface plasmon resonance coupled to carbon nanostructures as signal amplifiers.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer's Aβ peptide

1 reference

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reference URL

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Getting into the brain: liposome-based strategies for effective drug delivery across the blood-brain barrier

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer's therapy

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer's Disease

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide regulation of cofilin activity in the CNS: A novel therapeutic approach for treatment of multiple neurological disorders

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30336640

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biomimetics in drug delivery systems: A critical review.

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https://pubmed.ncbi.nlm.nih.gov/30336640

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody-functionalized polymer nanoparticle leading to memory recovery in Alzheimer's disease-like transgenic mouse model.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30336640

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle

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https://pubmed.ncbi.nlm.nih.gov/30336640

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex differences in Alzheimer disease — the gateway to precision medicine

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https://pubmed.ncbi.nlm.nih.gov/30336640

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanoparticle crossing of blood-brain barrier: a road to new therapeutic approaches to central nervous system diseases

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30336640

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.3390/PHARMACEUTICS10040190

1 reference

stated in

Europe PubMed Central

PMC publication ID

6321229

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30336640%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 April 2020

PMC publication ID

6321229

1 reference

stated in

Europe PubMed Central

PMC publication ID

6321229

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30336640%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 April 2020

PubMed publication ID

30336640

1 reference

stated in

Europe PubMed Central

PMC publication ID

6321229

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30336640%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 April 2020

 

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