Systematic identification of celastrol-binding proteins reveals that Shoc2 is inhibited by celastrol (Q58605081)

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scholarly article by Xiao-Pei Huang published in October 2018

• Systematic identification of Celastrol-binding proteins reveals that Shoc2 is inhibited by Celastrol

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English	Systematic identification of celastrol-binding proteins reveals that Shoc2 is inhibited by celastrol	scholarly article by Xiao-Pei Huang published in October 2018	Systematic identification of Celastrol-binding proteins reveals that Shoc2 is inhibited by Celastrol

Statements

instance of

scholarly article

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title

Systematic identification of celastrol-binding proteins reveals that Shoc2 is inhibited by celastrol (English)

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main subject

biophysics

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molecular biology

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author name string

Xiao-Pei Huang

series ordinal

1

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Ji-Kuai Chen

series ordinal

2

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Wei Xu

series ordinal

3

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Yi-Fan Dong

series ordinal

4

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Lang Yan

series ordinal

5

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Xiao-Fang Zhang

series ordinal

6

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Ya-Min Pan

series ordinal

7

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Wen-Jun Chang

series ordinal

8

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Jiang-Bo Zhu

series ordinal

9

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language of work or name

English

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publication date

17 October 2018

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published in

Bioscience Reports

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volume

38

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issue

6

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page(s)

BSR20181233

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copyright license

Creative Commons Attribution 4.0 International

start time

26 July 2019

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stated in

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

stated in

Europe PubMed Central

retrieved

11 June 2022

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6246769/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Apoptosis Induction in HL-60 Cells and Inhibition of Topoisomerase II by Triterpene Celastrol

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Surgical adjuvant therapy for colorectal cancer: current approaches and future directions

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

based on heuristic

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Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Hexamethylene bisacetamide (HMBA) simultaneously targets AKT and MAPK pathway and represses NF kappaB activity: implications for cancer therapy.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Celastrol causes apoptosis and cell cycle arrest in rat glioma cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Adjuvant chemotherapy use and adverse events among older patients with stage III colon cancer

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Endothelial SUR-8 acts in an ERK-independent pathway during atrioventricular cushion development.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

based on heuristic

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Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Celastrol isolated from Tripterygium regelii induces apoptosis through both caspase-dependent and -independent pathways in human breast cancer cells.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

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Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-catenin mediates the apoptosis induction effect of celastrol in HT29 cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer: the role of inflammation.

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

World Cancer Report 2014. Geneva, Switzerland: World Health Organization, International Agency for Research on Cancer, WHO Press, 2015.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioactive natural products in cancer prevention and therapy: Progress and promise

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The function of Shoc2: A scaffold and beyond

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Celastrol induces apoptosis in hepatocellular carcinoma cells via targeting ER-stress/UPR.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30333251

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1042/BSR20181233

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PMC publication ID

6246769

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PubMed publication ID

30333251

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