Potential Link between Amyloid β-Protein 42 and C-terminal Fragment γ 49–99 of β-Amyloid Precursor Protein (Q51837859)

13 April 2018

reason for preferred rank

title

Potential Link between Amyloid β-Protein 42 and C-terminal Fragment γ 49–99 of β-Amyloid Precursor Protein (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M211161200

26 December 2023

Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707272

26 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M211161200

26 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M211161200

26 December 2023

Hiroaki Misonou

5

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Christian Haass

9

object named as

Christian Haass

1 reference

13 April 2018

author name string

Toru Sato

1

1 reference

13 April 2018

Naoshi Dohmae

2

1 reference

13 April 2018

Yue Qi

3

1 reference

13 April 2018

Nobuto Kakuda

4

1 reference

13 April 2018

Rie Mitsumori

6

1 reference

13 April 2018

Hiroko Maruyama

7

1 reference

13 April 2018

Koji Takio

10

1 reference

13 April 2018

Maho Morishima-Kawashima

11

1 reference

13 April 2018

Shoichi Ishiura

12

1 reference

13 April 2018

Yasuo Ihara

13

1 reference

13 April 2018

Edward H. Koo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707272

26 December 2023

language of work or name

English

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publication date

21 April 2003

1 reference

13 April 2018

full work available at URL

http://www.jbc.org/article/S002192582086880X/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707272

https://api.elsevier.com/content/article/PII:S002192582086880X?httpAccept=text/xml

26 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M211161200

https://api.elsevier.com/content/article/PII:S002192582086880X?httpAccept=text/plain

26 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M211161200

https://syndication.highwire.org/content/doi/10.1074/jbc.M211161200

26 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M211161200

Journal of Biological Chemistry

26 December 2023

published in

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13 April 2018

volume

278

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13 April 2018

issue

27

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13 April 2018

page(s)

24294-24301

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13 April 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

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aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

21 January 2018

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PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin

21 January 2018

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Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

21 January 2018

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Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease

21 January 2018

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Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

21 January 2018

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gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

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Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

21 January 2018

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Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains

21 January 2018

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A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing

21 January 2018

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 January 2018

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

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Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

21 January 2018

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Distinct mechanisms by mutant presenilin 1 and 2 leading to increased intracellular levels of amyloid beta-protein 42 in Chinese hamster ovary cells

21 January 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

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A substrate-based difluoro ketone selectively inhibits Alzheimer's gamma-secretase activity.

21 January 2018

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Biochemical characterization of the gamma-secretase activity that produces beta-amyloid peptides

21 January 2018

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Presenilin 1 mutations activate gamma 42-secretase but reciprocally inhibit epsilon-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch

21 January 2018

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Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.

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Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

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Separation of presenilin function in amyloid beta-peptide generation and endoproteolysis of Notch

21 January 2018

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Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production

21 January 2018

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Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway

21 January 2018

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A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

21 January 2018

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Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide

21 January 2018

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Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1.

21 January 2018

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Elevated abeta42 in skeletal muscle of Alzheimer disease patients suggests peripheral alterations of AbetaPP metabolism.

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Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

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Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch

26 December 2023

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The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation

26 December 2023

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Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased A beta42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans

26 December 2023

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26 December 2023

Identifiers

1 reference

13 April 2018

1 reference

13 April 2018