The Receptor for Advanced Glycation Endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and Exploiting Common Ground for Novel Amyloidosis Therapies. (Q52583445)

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scientific article published on 17 April 2018

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English	The Receptor for Advanced Glycation Endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and Exploiting Common Ground for Novel Amyloidosis Therapies.	scientific article published on 17 April 2018

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29664151%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

The receptor for advanced glycation endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and exploiting common ground for novel amyloidosis therapies (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29664151%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

author name string

Julia Derk

2

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23 March 2020

publication date

1 July 2018

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23 March 2020

Protein Science

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23 March 2020

27

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23 March 2020

7

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23 March 2020

1166-1180

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23 March 2020

IAPP and type 1 diabetes: implications for immunity, metabolism and islet transplants

1 reference

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7 September 2018

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

1 reference

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Pyroglutamate and Isoaspartate modified Amyloid-Beta in ageing and Alzheimer's disease

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2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2018.

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Autophagy protects pancreatic beta cell mass and function in the setting of a high-fat and high-glucose diet.

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7 September 2018

The β-cell assassin: IAPP cytotoxicity

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Transplantation of human fetal pancreatic progenitor cells ameliorates renal injury in streptozotocin-induced diabetic nephropathy

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Islet Amyloid Polypeptide Membrane Interactions: Effects of Membrane Composition

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Molecular mechanisms of ROS production and oxidative stress in diabetes.

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Control of Insulin Secretion by Production of Reactive Oxygen Species: Study Performed in Pancreatic Islets from Fed and 48-Hour Fasted Wistar Rats

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Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics.

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7 September 2018

Autophagy is a major regulator of beta cell insulin homeostasis.

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Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

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The Possible Mechanism of Advanced Glycation End Products (AGEs) for Alzheimer's Disease

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Insulin granules. Insulin secretory granules control autophagy in pancreatic β cells

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Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model

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Rationally designed, nontoxic, nonamyloidogenic analogues of human islet amyloid polypeptide with improved solubility

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7 September 2018

Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity

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7 September 2018

Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy

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7 September 2018

Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes

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7 September 2018

Islet amyloid and type 2 diabetes: overproduction or inadequate clearance and detoxification?

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7 September 2018

Truncated and modified amyloid-beta species

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7 September 2018

Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice

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7 September 2018

Insulin gene mutations and diabetes

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7 September 2018

Autophagy protects against human islet amyloid polypeptide-associated apoptosis

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Inefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes

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The ability of insulin to inhibit the formation of amyloid by pro-islet amyloid polypeptide processing intermediates is significantly reduced in the presence of sulfated glycosaminoglycans

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7 September 2018

Apoptosis induced by islet amyloid polypeptide soluble oligomers is neutralized by diabetes-associated specific antibodies.

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7 September 2018

Advanced glycation end products of beta2-microglobulin in uremic patients as determined by high resolution mass spectrometry

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pH dependence of amylin fibrillization

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7 September 2018

Retracted: Glycation Accelerates Fibrillization of the Amyloidogenic W7FW14F Apomyoglobin

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7 September 2018

Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction.

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7 September 2018

Islet amyloid polypeptide toxicity and membrane interactions

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CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

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Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models

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Alzheimer disease and diabetes mellitus: do they have anything in common?

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7 September 2018

Induction of receptor for advanced glycation end products by insufficient leptin action triggers pancreatic β-cell failure in type 2 diabetes

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7 September 2018

Mechanisms of islet amyloidosis toxicity in type 2 diabetes

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7 September 2018

Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes

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7 September 2018

Advanced glycation end products and neurodegenerative diseases: mechanisms and perspective

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The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane

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7 September 2018

Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans

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7 September 2018

Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications

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7 September 2018

Signal Transduction in Receptor for Advanced Glycation End Products (RAGE): SOLUTION STRUCTURE OF C-TERMINAL RAGE (ctRAGE) AND ITS BINDING TO mDia1

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7 September 2018

Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice

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7 September 2018

cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.

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7 September 2018

Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion

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Transmission of prions within the gut and towards the central nervous system

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IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.

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7 September 2018

Islet amyloid polypeptide, islet amyloid, and diabetes mellitus

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Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment

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AGEs decrease insulin synthesis in pancreatic β-cell by repressing Pdx-1 protein expression at the post-translational level

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Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets.

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7 September 2018

RAGE: the beneficial and deleterious effects by diverse mechanisms of actions

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Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.

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Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species

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Inhibition of the receptor for advanced glycation endproducts (RAGE) protects pancreatic β-cells

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RAGE ligands induce apoptotic cell death of pancreatic β-cells via oxidative stress

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Structural Basis for Ligand Recognition and Activation of RAGE

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The 1.5 Å Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE) Ectodomains Reveals Unique Features Determining Ligand Binding

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Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

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7 September 2018

Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions

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Central amylin acts as an adiposity signal to control body weight and energy expenditure

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Insights into amylin-leptin synergy

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Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.

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The role of amylin in the control of energy homeostasis

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Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY).

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The sour side of neurodegenerative disorders: the effects of protein glycation.

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7 September 2018

Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?

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7 September 2018

Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway

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7 September 2018

Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention

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7 September 2018

Calcium-activated calpain-2 is a mediator of beta cell dysfunction and apoptosis in type 2 diabetes

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7 September 2018

Recent advances in understanding leptin signaling and leptin resistance

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7 September 2018

Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide

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7 September 2018

A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides

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7 September 2018

The role of RAGE in amyloid-beta peptide-mediated pathology in Alzheimer's disease.

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7 September 2018

Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process

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7 September 2018

The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes

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7 September 2018

Autophagy in human type 2 diabetes pancreatic beta cells.

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7 September 2018

Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress

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7 September 2018

RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation.

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7 September 2018

Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis

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7 September 2018

A role for helical intermediates in amyloid formation by natively unfolded polypeptides?

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7 September 2018

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

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7 September 2018

Amyloid oligomers in diabetic and nondiabetic human pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Structural classification of toxic amyloid oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Clinical review: The role of advanced glycation end products in progression and complications of diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Amyloid formation by pro-islet amyloid polypeptide processing intermediates: examination of the role of protein heparan sulfate interactions and implications for islet amyloid formation in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Proinsulin maturation, misfolding, and proteotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Impairment of the ubiquitin-proteasome pathway is a downstream endoplasmic reticulum stress response induced by extracellular human islet amyloid polypeptide and contributes to pancreatic beta-cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Direct detection of transient alpha-helical states in islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

High levels of soluble receptor for advanced glycation end products may be a marker of extreme longevity in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

In vitro inhibition of transthyretin aggregate-induced cytotoxicity by full and peptide derived forms of the soluble receptor for advanced glycation end products (RAGE)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

The role of His-18 in amyloid formation by human islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: is there a critical amyloidogenic domain in human IAPP?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Lipid membranes modulate the structure of islet amyloid polypeptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Glycation induces formation of amyloid cross-beta structure in albumin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Full-length rat amylin forms fibrils following substitution of single residues from human amylin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Advanced glycation end products (AGE) and their receptor (RAGE) in the brain of patients with Creutzfeldt-Jakob disease with prion plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Advanced glycation end product-induced apoptosis and overexpression of vascular endothelial growth factor and monocyte chemoattractant protein-1 in human-cultured mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Protein "AGEing"--cytotoxicity of a glycated protein increases with its degree of AGE-modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Familial amyloid polyneuropathy: receptor for advanced glycation end products-dependent triggering of neuronal inflammatory and apoptotic pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Series introduction: multiligand receptors and human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Glucose-modified proteins modulate essential functions and apoptosis of polymorphonuclear leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet beta-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Advanced glycation end-products: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Identification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implications for islet amyloid formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Abeta-induced inflammatory processes in microglia cells of APP23 transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Neurotoxicity of advanced glycation end-products for cultured cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

The biology of the receptor for advanced glycation end products and its ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Advanced glycation end products induce apoptosis and procoagulant activity in cultured human umbilical vein endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Neurotoxicity of methylglyoxal and 3-deoxyglucosone on cultured cortical neurons: synergism between glycation and oxidative stress, possibly involved in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Insulin-stimulated insulin secretion in single pancreatic beta cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Cytotoxicity of advanced glycation endproducts is mediated by oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Cell activation by glycated proteins. AGE receptors, receptor recognition factors and functional classification of AGEs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Identification of polymorphisms in the receptor for advanced glycation end products (RAGE) gene: prevalence in type 2 diabetes and ethnic groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Contribution of advanced glycosylation to the amyloidogenicity of islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Long-term effects of aminoguanidine on insulin release and biosynthesis: evidence that the formation of advanced glycosylation end products inhibits B cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Advanced glycation end products contribute to amyloidosis in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

7 September 2018

Toxic action of advanced glycation end products on cultured retinal capillary pericytes and endothelial cells: relevance to diabetic retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6032365

30 November 2018

Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pore formation by the cytotoxic islet amyloid peptide amylin

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoguanidine and the effects of modified LDL on cultured retinal capillary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-type plasminogen activator is a multiligand cross-beta structure receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

De-N-glycosylation or G82S mutation of RAGE sensitizes its interaction with advanced glycation endproducts

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is type 2 diabetes an amyloidosis and does it really matter (to patients)?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual effect of advanced glycation end products in pancreatic islet apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29664151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/PRO.3425

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29664151%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

release_uvrjw2mxmndilgt6segm6dr2ju

1 reference

https://api.fatcat.wiki/v0/release/uvrjw2mxmndilgt6segm6dr2ju

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29664151%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29664151%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

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