Diverse roles of TGF-β receptor II in renal fibrosis and inflammation in vivo and in vitro. (Q52619754)

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19 January 2020

title

Diverse roles of TGF-β receptor II in renal fibrosis and inflammation in vivo and in vitro (English)

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19 January 2020

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1

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Hai Yong Chen

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Hui Y Lan

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author name string

Xiao Ru Huang

2

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19 January 2020

Jun Xiao

3

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Xiang Zhong

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Arthur C K Chung

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publication date

22 February 2012

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volume

227

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issue

2

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19 January 2020

page(s)

175-188

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TGF-beta signaling in renal disease

19 January 2020

cites work

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Transforming growth factor-beta and Smad signalling in kidney diseases.

21 January 2018

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Regulation of immune responses by TGF-beta

21 January 2018

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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

21 January 2018

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Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease

21 January 2018

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Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7.

21 January 2018

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Latent TGF-beta1 protects against crescentic glomerulonephritis

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

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Transcriptional control by the TGF-beta/Smad signaling system

21 January 2018

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Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

21 January 2018

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Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.

21 January 2018

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Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice.

21 January 2018

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Smad3 deficiency attenuates renal fibrosis, inflammation,and apoptosis after unilateral ureteral obstruction

21 January 2018

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Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney.

21 January 2018

1 reference

Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model

21 January 2018

1 reference

Blockade of NFkappaB activation and renal inflammation by ultrasound-mediated gene transfer of Smad7 in rat remnant kidney.

21 January 2018

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Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice.

21 January 2018

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The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential

21 January 2018

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TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

21 January 2018

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Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract.

21 January 2018

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Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable

21 January 2018

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Essential role of Smad3 in angiotensin II-induced vascular fibrosis

21 January 2018

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Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling

21 January 2018

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

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Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis

21 January 2018

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Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis

21 January 2018

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Bladder stromal loss of transforming growth factor receptor II decreases fibrosis after bladder obstruction

21 January 2018

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Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice

21 January 2018

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TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis.

21 January 2018

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Activation of ERK in renal fibrosis after unilateral ureteral obstruction: modulation by antioxidants.

21 January 2018

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A reduction of unilateral ureteral obstruction-induced renal fibrosis by a therapy combining valsartan with aliskiren.

21 January 2018

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Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

21 January 2018

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Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.3976

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19 January 2020

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