Histone/protein deacetylase inhibitor therapy for enhancement of Foxp3+ T-regulatory cell function posttransplantation. (Q52722715)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29603600%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

Histone/protein deacetylase inhibitor therapy for enhancement of Foxp3+ T-regulatory cell function posttransplantation (English)

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22 March 2020

2

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22 March 2020

Satinder Dahiya

4

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22 March 2020

author name string

L Wang

1

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22 March 2020

T Akimova

3

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22 March 2020

R Han

5

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22 March 2020

A Samanta

6

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22 March 2020

M H Levine

7

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22 March 2020

W W Hancock

8

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22 March 2020

language of work or name

English

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publication date

21 April 2018

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American Journal of Transplantation

22 March 2020

published in

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22 March 2020

volume

18

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22 March 2020

issue

7

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22 March 2020

page(s)

1596-1603

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Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

22 March 2020

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Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60.

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Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function.

29 September 2018

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29 September 2018

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Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity

29 September 2018

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Inhibition of Histone Deacetylase 6 Reveals a Potent Immunosuppressant Effect in Models of Transplantation.

29 September 2018

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Isoform-Selective HDAC Inhibitor Therapy for Transplantation: Are We Ready for HDAC6?

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29 September 2018

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HDAC5 controls the functions of Foxp3(+) T-regulatory and CD8(+) T cells

29 September 2018

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Thiol-Based Potent and Selective HDAC6 Inhibitors Promote Tubulin Acetylation and T-Regulatory Cell Suppressive Function

29 September 2018

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Standardization, Evaluation, and Area-Under-Curve Analysis of Human and Murine Treg Suppressive Function

29 September 2018

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Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation.

29 September 2018

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Class-specific histone/protein deacetylase inhibition protects against renal ischemia reperfusion injury and fibrosis formation

29 September 2018

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Sumoylation of HDAC2 promotes NF-κB-dependent gene expression.

29 September 2018

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Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival

29 September 2018

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FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.

29 September 2018

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DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.

29 September 2018

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Computational design of a time-dependent histone deacetylase 2 selective inhibitor

29 September 2018

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Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function

29 September 2018

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Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60.

29 September 2018

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Erasers of histone acetylation: the histone deacetylase enzymes

29 September 2018

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Targeting sirtuin-1 alleviates experimental autoimmune colitis by induction of Foxp3+ T-regulatory cells

29 September 2018

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Effects of histone deacetylase inhibitors on alloresponses.

29 September 2018

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Mbd2 promotes foxp3 demethylation and T-regulatory-cell function

29 September 2018

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Inhibition of p300 impairs Foxp3⁺ T regulatory cell function and promotes antitumor immunity.

29 September 2018

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Differing effects of rapamycin or calcineurin inhibitor on T-regulatory cells in pediatric liver and kidney transplant recipients

29 September 2018

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Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition

29 September 2018

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Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function

29 September 2018

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Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms.

29 September 2018

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Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function

29 September 2018

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Second-generation histone deacetylase 6 inhibitors enhance the immunosuppressive effects of Foxp3+ T-regulatory cells.

29 September 2018

1 reference

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Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells

29 September 2018

1 reference

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Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6035084

Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6035084

Chemical phylogenetics of histone deacetylases

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6035084

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6035084

Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6035084

Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells

29 September 2018

1 reference

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Resistance of Foxp3+ regulatory T cells to Nur77-induced apoptosis promotes allograft survival

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6035084

Deacetylase inhibition promotes the generation and function of regulatory T cells.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6035084

FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression

29 September 2018

1 reference

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Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation

29 September 2018

1 reference

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FOXP3 controls regulatory T cell function through cooperation with NFAT

29 September 2018

1 reference

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Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors

29 September 2018

1 reference

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

29 September 2018

1 reference

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

29 September 2018

1 reference

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

29 September 2018

1 reference

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

29 September 2018

1 reference

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Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

29 September 2018

1 reference

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29 September 2018

Identifiers

DOI

10.1111/AJT.14749

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29603600%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29603600%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

29603600

1 reference