Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells. (Q52828045)

8 May 2018

title

Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells. (English)

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8 May 2018

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Agochiya M

1

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8 May 2018

Brunton VG

2

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8 May 2018

Owens DW

3

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8 May 2018

Parkinson EK

4

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8 May 2018

Paraskeva C

5

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8 May 2018

Keith WN

6

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8 May 2018

Frame MC

7

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8 May 2018

language of work or name

English

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publication date

1 October 1999

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8 May 2018

published in

Oncogene

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8 May 2018

volume

18

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8 May 2018

issue

41

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8 May 2018

page(s)

5646-5653

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8 May 2018

describes a project that uses

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Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Interaction of focal adhesion kinase with cytoskeletal protein talin

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Mapping of the focal adhesion kinase (Fadk) gene to mouse chromosome 15 and human chromosome 8.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Inhibition of pp125FAK in cultured fibroblasts results in apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAK and dynamin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Signal transduction through integrins: a central role for focal adhesion kinase?

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Focal adhesion kinase and associated proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Direct association of pp125FAK with paxillin, the focal adhesion-targeting mechanism of pp125FAK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Cleavage of focal adhesion kinase by caspases during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

Impairment of mobility in endodermal cells by FAK deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

7 January 2021

Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

7 January 2021

Interphase cytogenetic analysis of erbB2 and topollα co‐amplification in invasive breast cancer and polysomy of chromosome 17 in ductal carcinoma in situ

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

7 January 2021

The radiosensitivity of cultured human and mouse keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

7 January 2021

Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202957

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202957

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8 May 2018

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8 May 2018