Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation. (Q53089642)

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English	Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation.	scientific article

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scholarly article

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11 May 2018

http://europepmc.org/abstract/MED/24048439

Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation. (English)

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PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/24048439

apoptotic process

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9

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13 June 2020

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13 June 2020

author name string

Wei-Ting Wang

1

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13 June 2020

Yen-Hui Chen

2

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13 June 2020

Jui-Ling Hsu

3

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13 June 2020

Wohn-Jenn Leu

4

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13 June 2020

Chia-Chun Yu

5

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13 June 2020

She-Hung Chan

6

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13 June 2020

Lih-Ching Hsu

8

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13 June 2020

publication date

19 September 2013

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11 May 2018

http://europepmc.org/abstract/MED/24048439

Naunyn-Schmiedeberg's Archives of Pharmacology

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13 June 2020

387

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13 June 2020

1

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13 June 2020

33-45

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13 June 2020

Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue.

1 reference

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21 January 2018

BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma

1 reference

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21 January 2018

Histamine and histamine receptor antagonists in cancer biology

1 reference

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21 January 2018

Bcl-xL is overexpressed in hormone-resistant prostate cancer and promotes survival of LNCaP cells via interaction with proapoptotic Bak.

1 reference

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21 January 2018

Proteins of the bcl-2 family in apoptosis signalling: from mechanistic insights to therapeutic opportunities.

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Upregulation of BAK by butyrate in the colon is associated with increased Sp3 binding.

1 reference

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21 January 2018

Induction of apoptosis by the Bcl-2 homologue Bak

1 reference

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21 January 2018

The Bcl2 family: regulators of the cellular life-or-death switch

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21 January 2018

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

1 reference

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21 January 2018

Hormone-refractory prostate cancer: a multi-step and multi-event process

1 reference

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Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis

1 reference

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21 January 2018

Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level

1 reference

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21 January 2018

Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak.

1 reference

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21 January 2018

Delineation of the caspase-9 signaling cascade

1 reference

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H1-receptor antagonists terfenadine and loratadine inhibit spontaneous growth of neoplastic mast cells

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H1 histamine receptor antagonists induce genotoxic and caspase-2-dependent apoptosis in human melanoma cells

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Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca2+ homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors.

1 reference

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21 January 2018

Up-regulation of Bak and Bim via JNK downstream pathway in the response to nitric oxide in human glioblastoma cells

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Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak

1 reference

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21 January 2018

The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells

1 reference

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21 January 2018

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

1 reference

https://api.crossref.org/works/10.1007%2FS00210-013-0912-X

21 January 2018

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

1 reference

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21 January 2018

Emerging mitochondrial signaling mechanisms in physiology, aging processes, and as drug targets

1 reference

https://api.crossref.org/works/10.1007%2FS00210-013-0912-X

21 January 2018

Mechanism underlying histamine-induced intracellular Ca2+ movement in PC3 human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00210-013-0912-X

21 January 2018

Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells

1 reference

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21 January 2018

Role of Bax in quercetin-induced apoptosis in human prostate cancer cells

1 reference

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21 January 2018

Involvement of caspase 3-activated DNase in internucleosomal DNA cleavage induced by diverse apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1007%2FS00210-013-0912-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-013-0912-X

21 January 2018

Retracted: Bak Compensated for Bax in p53-null Cells to Release Cytochrome c for the Initiation of Mitochondrial Signaling during Withanolide D-Induced Apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00210-013-0912-X

21 January 2018

A pivotal role for Mcl-1 in Bortezomib-induced apoptosis

1 reference

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21 January 2018

H1-receptor antagonists: clinical pharmacology and therapeutics

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New colorimetric cytotoxicity assay for anticancer-drug screening

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DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment.

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A dual antagonist for chemokine CCR3 receptor and histamine H1 receptor

1 reference

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Mitochondrial intermembrane proteins in cell death

1 reference

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

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Molecular biology of Bax and Bak activation and action

1 reference

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Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation.

1 reference

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Mcl-1: a highly regulated cell death and survival controller

1 reference

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Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy.

1 reference

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21 January 2018

Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas.

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Antiproliferative effect in human prostatic smooth muscle cells by nitric oxide donor

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/24048439

12 December 2020

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Prognostic significance of Bcl-2 in clinically localized prostate cancer

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Mechanisms of p53-dependent apoptosis

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Resistance to apoptosis in prostate cancer cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic overview of oral second-generation H1 antihistamines.

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Apoptosis of human T-cell acute lymphoblastic leukemia cells by diphenhydramine, an H1 histamine receptor antagonist.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00210-013-0912-X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24048439%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24048439%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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