A novel genetic score model of UGT1A1 and TGFB pathway as predictor of severe irinotecan-related diarrhea in metastatic colorectal cancer patients. (Q53105272)

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scientific article published on 9 May 2016

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English	A novel genetic score model of UGT1A1 and TGFB pathway as predictor of severe irinotecan-related diarrhea in metastatic colorectal cancer patients.	scientific article published on 9 May 2016

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

A novel genetic score model of UGT1A1 and TGFB pathway as predictor of severe irinotecan-related diarrhea in metastatic colorectal cancer patients. (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

0 references

colorectal cancer

1 reference

based on heuristic

inferred from title

metastatic colon cancer

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based on heuristic

inferred from title

author name string

Jing Li

1

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Qianqian Yu

2

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Shengling Fu

3

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Min Xu

4

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Tao Zhang

5

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Conghua Xie

6

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Jueping Feng

7

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Jigui Chen

8

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Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Aihua Zang

9

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Yixin Cai

10

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Qiang Fu

11

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Shan Liu

12

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Mingsheng Zhang

13

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Qiu Hong

14

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Liu Huang

15

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Xianglin Yuan

16

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

publication date

9 May 2016

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Journal of Cancer Research and Clinical Oncology

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Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

142

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PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

7

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Europe PubMed Central

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11 May 2018

http://europepmc.org/abstract/MED/27160286

1621-1628

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Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

Transforming growth factor-β in the gastrointestinal and hepatic tumor microenvironment.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Distribution of selected gene polymorphisms of UGT1A1 in a Saudi population.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Dietary transforming growth factor-beta 2 (TGF-β2) supplementation reduces methotrexate-induced intestinal mucosal injury in a rat.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11).

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

UGT1A1*6 polymorphisms are correlated with irinotecan-induced toxicity: a system review and meta-analysis in Asians

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Protection against chemotherapy induced mucositis by TGF-beta(2) in childhood cancer patients: results from a randomized cross-over study.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Irinotecan causes severe small intestinal damage, as well as colonic damage, in the rat with implanted breast cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Dose-dependent association between UGT1A1*28 polymorphism and irinotecan-induced diarrhoea: a meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Rebamipide attenuates 5-Fluorouracil-induced small intestinal mucositis in a mouse model

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer: the role of inflammation.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

The chemokine CXCL9 exacerbates chemotherapy-induced acute intestinal damage through inhibition of mucosal restitution

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Genetic variation and gastric cancer risk: a field synopsis and meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

TGF-β: duality of function between tumor prevention and carcinogenesis.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

TGF-β limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

A molecular mechanism for the differential regulation of TGF-beta1 expression due to the common SNP -509C-T (c. -1347C > T).

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Prevalence of the UGT1A1*6 (c.211G>A) Polymorphism and Prediction of Irinotecan Toxicity in Iranian Populations of Different Ethnicities

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study

1 reference

https://api.crossref.org/works/10.1007%2FS00432-016-2176-6

21 January 2018

Relationship between UGT1A1*6/*28 polymorphisms and severe toxicities in Chinese patients with pancreatic or biliary tract cancer treated with irinotecan-containing regimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/27160286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Milk casein-based diet containing TGF-beta controls the inflammatory reaction in the HLA-B27 transgenic rat model

1 reference

https://pubmed.ncbi.nlm.nih.gov/27160286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel system for predicting the toxicity of irinotecan based on statistical pattern recognition with UGT1A genotypes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27160286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11

1 reference

https://pubmed.ncbi.nlm.nih.gov/27160286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relevance of irinotecan hydrochloride-induced diarrhea to the level of prostaglandin E2 and water absorption of large intestine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/27160286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27160286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of cytokines (TNF-α, IL-1β and KC) in the pathogenesis of CPT-11-induced intestinal mucositis in mice: effect of pentoxifylline and thalidomide

1 reference

https://pubmed.ncbi.nlm.nih.gov/27160286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of UGT1A1 gene polymorphisms on irinotecan-based regimens as the treatment in metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27160286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

F-SNP: computationally predicted functional SNPs for disease association studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/27160286

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00432-016-2176-6

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/27160286

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