Specificity of mechanisms for plaque removal after A beta immunotherapy for Alzheimer disease. (Q53260055)

12 May 2018

title

Specificity of mechanisms for plaque removal after A beta immunotherapy for Alzheimer disease. (English)

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12 May 2018

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Haruhiko Akiyama

1

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12 May 2018

Patrick L McGeer

series ordinal

2

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12 May 2018

language of work or name

English

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publication date

1 February 2004

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12 May 2018

published in

Nature Medicine

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12 May 2018

volume

10

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12 May 2018

issue

2

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12 May 2018

page(s)

117-8; author reply 118-9

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12 May 2018

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

cites work

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The amino-terminally truncated forms of amyloid beta-protein in brain macrophages in the ischemic lesions of Alzheimer's disease patients

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Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein

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Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis.

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Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes

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Inflammation, autotoxicity and Alzheimer disease

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Complement activation by beta-amyloid in Alzheimer disease

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Activation of the classical complement pathway in brain tissue of Alzheimer patients

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Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease

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Complement regulators C1 inhibitor and CD59 do not significantly inhibit complement activation in Alzheimer disease

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The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation

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Is there a future for vaccination as a treatment for Alzheimer's disease?

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Brain microglia constitutively express beta-2 integrins

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Identifiers

DOI

10.1038/NM0204-117

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12 May 2018

1 reference

12 May 2018