Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. (Q53482421)

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scientific article published on 18 April 2008

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English	Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells.	scientific article published on 18 April 2008

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6 January 2020

Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells (English)

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6 January 2020

ataxia telangiectasia

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based on heuristic

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Dragan Marinkovic

5

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6 January 2020

Marcos Grisotto

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6 January 2020

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Safak Yalcin

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6 January 2020

Xin Zhang

2

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6 January 2020

Julia P Luciano

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6 January 2020

Sathish Kumar Mungamuri

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6 January 2020

Cécile Vercherat

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6 January 2020

Abby Sarkar

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6 January 2020

Reshma Taneja

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6 January 2020

Saghi Ghaffari

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18 April 2008

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6 January 2020

Journal of Biological Chemistry

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6 January 2020

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6 January 2020

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6 January 2020

25692-25705

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6 January 2020

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Foxo3 is required for the regulation of oxidative stress in erythropoiesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

FOXO transcription factors at the interface between longevity and tumor suppression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Preselection of retrovirally transduced bone marrow avoids subsequent stem cell gene silencing and age-dependent extinction of expression of human beta-globin in engrafted mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Forkhead transcription factors contribute to execution of the mitotic programme in mammals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Stem cell repopulation efficiency but not pool size is governed by p27(kip1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Principles of tumor suppression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Proliferative kinetics and differentiation of murine blast cell colonies in culture: evidence for variable G0 periods and constant doubling rates of early pluripotent hemopoietic progenitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Free radicals in the physiological control of cell function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Functional interaction between FOXO3a and ATM regulates DNA damage response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800517200

21 January 2018

Identifiers

10.1074/JBC.M800517200

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18424439%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18424439%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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