An understanding of the role of enzyme localization of the liver on metabolite kinetics: a computer simulation. (Q53876522)

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scientific article published in October 1983

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English	An understanding of the role of enzyme localization of the liver on metabolite kinetics: a computer simulation.	scientific article published in October 1983

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instance of

scholarly article

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Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

title

An understanding of the role of enzyme localization of the liver on metabolite kinetics: a computer simulation. (English)

1 reference

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Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

main subject

computer simulation

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author name string

K S Pang

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

R N Stillwell

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

publication date

1 October 1983

1 reference

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Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

published in

Journal of Pharmacokinetics and Pharmacodynamics

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stated in

Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

volume

11

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Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

issue

5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

page(s)

451-468

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Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

cites work

Clearance concepts in pharmacokinetics

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1007%2FBF01062205

retrieved

21 January 2018

Hepatic clearance of drugs. II. Experimental evidence for acceptance of the “well-stirred” model over the “parallel tube” model using lidocaine in the perfused rat liverin situ preparation

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1007%2FBF01062205

retrieved

21 January 2018

Hepatic clearance of drugs. III. Additional experimental evidence supporting the "well-stirred" model, using metabolite (MEGX) generated from lidocaine under varying hepatic blood flow rates and linear conditions in the perfused rat liver in situ pr

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1007%2FBF01062205

retrieved

21 January 2018

Sequential first-pass elimination of a metabolite derived from a precursor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of acetaminophen and phenacetin by isolated rat hepatocytes. A system in which the spatial organization inherent in the liver is disrupted

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

retrieved

12 December 2020

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Lidocaine disposition kinetics in monkey and man. I. Prediction by a perfusion model.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

based on heuristic

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Factors affecting drug metabolism

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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Thiopental Pharmacokinetics

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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The theory and applications of the exchange of inert gas at the lungs and tissues

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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Michaelis-Menten kinetics of galactose elimination by the isolated perfused pig liver

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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Cellular necrosis in the liver induced and modified by drugs

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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inferred from PubMed ID database lookup

Effect of sinusoidal perfusion on galactose elimination kinetics in perfused rat liver

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rates of sulfation and glucuronidation of 7-hydroxycoumarin in periportal and pericentral regions of the liver lobule

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate Pharmacokinetics

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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inferred from PubMed ID database lookup

Immunohistochemical localizations of cytochromes P-450 in rat liver

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of metabolite formation and elimination in the perfused rat liver preparation: differences between the elimination of preformed acetaminophen and acetaminophen formed from phenacetin

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol elimination kinetics in human liver and pig liver in vivo

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin and phenobarbital on the occurrence and distribution of four cytochrome P-450 isozymes in rabbit kidney, lung, and liver

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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Commentary: a physiological approach to hepatic drug clearance

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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Retrograde perfusion to probe the heterogeneous distribution of hepatic drug metabolizing enzymes in rats

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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inferred from PubMed ID database lookup

Effects of route of administration and blood flow on hepatic drug elimination

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

retrieved

12 December 2020

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Normal and retrograde perfusion to probe the zonal distribution of sulfation and glucuronidation activities of harmol in the perfused rat liver preparation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolite kinetics: formation of acetaminophen from deuterated and nondeuterated phenacetin and acetanilide on acetaminophen sulfation kinetics in the perfused rat liver preparation.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of sulfate conjugation of N-hydroxy-2-acetylaminofluorene in isolated perfused rat liver and in the rat in vivo by pentachlorophenol and low sulfate

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6668553

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12 December 2020

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Identifiers

DOI

10.1007/BF01062205

1 reference

stated in

Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

PubMed publication ID

6668553

1 reference

stated in

Europe PubMed Central

PubMed publication ID

6668553

retrieved

21 May 2018

reference URL

http://europepmc.org/abstract/MED/6668553

 

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