SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway. (Q53959197)

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7 January 2020

title

SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway (English)

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7 January 2020

author name string

Eva Hug

2

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7 January 2020

Sonja Meixlsperger

3

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7 January 2020

Ji-Hye Paik

4

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7 January 2020

Michael Reth

6

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7 January 2020

Hassan Jumaa

7

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7 January 2020

language of work or name

English

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publication date

1 June 2008

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7 January 2020

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7 January 2020

volume

9

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7 January 2020

issue

6

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7 January 2020

page(s)

623-631

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Regulation of V(D)J recombination

7 January 2020

cites work

1 reference

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

21 January 2018

1 reference

The role of the non-homologous end-joining pathway in lymphocyte development

21 January 2018

1 reference

B cell signaling and tumorigenesis

21 January 2018

1 reference

The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion.

21 January 2018

1 reference

Receptor editing is the main mechanism of B cell tolerance toward membrane antigens

21 January 2018

1 reference

Basal immunoglobulin signaling actively maintains developmental stage in immature B cells

21 January 2018

1 reference

The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells.

21 January 2018

1 reference

Phospholipase Cgamma2 contributes to light-chain gene activation and receptor editing

21 January 2018

1 reference

Modification of ligand-independent B cell receptor tonic signals activates receptor editing in immature B lymphocytes

21 January 2018

1 reference

Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection.

21 January 2018

1 reference

The activation of Akt/PKB signaling pathway and cell survival.

21 January 2018

1 reference

Forkhead-box transcription factors and their role in the immune system

21 January 2018

1 reference

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

21 January 2018

1 reference

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

21 January 2018

1 reference

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

21 January 2018

1 reference

Direct control of the Forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells.

21 January 2018

1 reference

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

21 January 2018

1 reference

Role of translocation in the activation and function of protein kinase B

21 January 2018

1 reference

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

21 January 2018

1 reference

FOXO3a induces differentiation of Bcr-Abl-transformed cells through transcriptional down-regulation of Id1.

21 January 2018

1 reference

Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

21 January 2018

1 reference

Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair

21 January 2018

1 reference

Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a

21 January 2018

1 reference

Testing gene function early in the B cell lineage in mb1-cre mice

21 January 2018

1 reference

BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway

21 January 2018

1 reference

Phosphoinositide 3-kinase signaling is essential for ABL oncogene-mediated transformation of B-lineage cells

21 January 2018

1 reference

A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells

21 January 2018

1 reference

Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

21 January 2018

1 reference

Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle.

21 January 2018

1 reference

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

21 January 2018

1 reference

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

Cd19-dependent activation of Akt kinase in B-lymphocytes

21 January 2018

1 reference

Syk tyrosine kinase required for mouse viability and B-cell development

21 January 2018

1 reference

CD19 function in early and late B cell development. II. CD19 facilitates the pro-B/pre-B transition

21 January 2018

1 reference

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

21 January 2018

1 reference

Impaired light chain allelic exclusion and lack of positive selection in immature B cells expressing incompetent receptor deficient of CD19.

21 January 2018

1 reference

A leucine zipper in the N terminus confers membrane association to SLP-65

21 January 2018

1 reference

Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein

21 January 2018

1 reference

Impaired receptor editing in the primary B cell repertoire of BASH-deficient mice

21 January 2018

1 reference

7 January 2021

Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a

1 reference

7 January 2021

Conventional light chains inhibit the autonomous signaling capacity of the B cell receptor

1 reference

7 January 2021

A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle

1 reference

7 January 2021

PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways

1 reference

7 January 2021

CD19 of B Cells as a Surrogate Kinase Insert Region to Bind Phosphatidylinositol 3-Kinase

1 reference

7 January 2021

CD19 regulates positive selection and maturation in B lymphopoiesis: lack of CD19 imposes developmental arrest of immature B cells and consequential stimulation of receptor editing

1 reference

7 January 2021

The Ig-alpha ITAM is required for efficient differentiation but not proliferation of pre-B cells

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI.1616

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18488031%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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