Effects of aminofluorene and acetylaminofluorene DNA adducts on transcriptional elongation by RNA polymerase II (Q64382839)

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R P Fuchs

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D Reines

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P C Hanawalt

Journal of Biological Chemistry

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language of work or name

English

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publication date

3 May 1996

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published in

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volume

271

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issue

18

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page(s)

10588-94

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uvr Genes function differently in repair of acetylaminofluorene and aminofluorene DNA adducts

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Nascent RNA cleavage by arrested RNA polymerase II does not require upstream translocation of the elongation complex on DNA

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RNA polymerase II elongation complex. Elongation complexes purified using an anti-RNA antibody do not contain initiation factor alpha

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Transcript elongation and termination are competitive kinetic processes

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Stranded in an active gene

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Acetylaminofluorene and aminofluorene adducts inhibit in vitro transcription of a Xenopus 5S RNA gene only when located on the coding strand

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