Alkylation of deoxyribonucleic acid in vivo in various organs of C57BL mice by the carcinogens N-methyl-N-nitrosourea, N-ethyl-N-nitrosourea and ethyl methanesulphonate in relation to induction of thymic lymphoma. Some applications of high-pressure (Q67427068)

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scientific article published on 01 September 1978

Language	Label	Description	Also known as
English	Alkylation of deoxyribonucleic acid in vivo in various organs of C57BL mice by the carcinogens N-methyl-N-nitrosourea, N-ethyl-N-nitrosourea and ethyl methanesulphonate in relation to induction of thymic lymphoma. Some applications of high-pressure	scientific article published on 01 September 1978

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:728073%20AND%20SRC:MED&resulttype=core&format=json

13 September 2019

Alkylation of deoxyribonucleic acid in vivo in various organs of C57BL mice by the carcinogens N-methyl-N-nitrosourea, N-ethyl-N-nitrosourea and ethyl methanesulphonate in relation to induction of thymic lymphoma. Some applications of high-pressure liquid chromatography (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:728073%20AND%20SRC:MED&resulttype=core&format=json

13 September 2019

author name string

J V Frei

1

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13 September 2019

D H Swenson

2

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13 September 2019

W Warren

3

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13 September 2019

P D Lawley

4

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13 September 2019

publication date

1 September 1978

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13 September 2019

Biochemical Journal

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13 September 2019

174

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13 September 2019

3

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13 September 2019

1031-1044

1 reference

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13 September 2019

A new method for the isolation of deoxyribonucleic acids; evidence on the nature of bonds between deoxyribonucleic acid and protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for two-step binding of reduced nicotinamide-adenine dinucleotide to aldehyde dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkylation of deoxyribonucleic acid by carcinogens dimethyl sulphate, ethyl methanesulphonate, N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea. Relative reactivity of the phosphodiester site thymidylyl(3′-5′)thymidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stability of methyl and ethyl phosphotriesters in DNA in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excision of O6-methylguanine from DNA of various mouse tissues following a single injection of N-methyl-Nitrosourea

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkylation of rat liver DNA by dimethylnitrosamine: effect of dosage on O6-methylguanine levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

All oxygens in nucleic acids react with carcinogenic ethylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylated purines in the deoxyribonucleic acid of various Syrian-golden-hamster tissues after administration of a hepatocarcinogenic dose of dimethylnitrosamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair excision of alkylated bases from DNA in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the methyl phosphotriester of thymidylyl (3',5')thymidine as a product from reaction of DNA with the carcinogen N-methyl-N-nitrosourea

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of dose and schedule of methylnitrosourea on incidence of malignant lymphoma in adult female mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N'-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological implications of the instability of the N-glycosidic bone of 3-methyldeoxyadenosine in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity, tissue changes, and tumor induction in inbred Swiss mice by methylnitrosamine and -amide compounds.

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and identification of products from alkylation of nucleic acids: ethyl- and isopropyl-purines

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of different classes of ethylating agents toward various sites of HeLa cell DNA in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific excision of ethylated purines from DNA of Escherichia coli treated with N-ethyl-N-nitrosourea

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction of N-methyl-N-nitrosourea (MNUA) with 32P-labelled DNA: evidence for formation of phosphotriesters

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An assay for phosphotriester formation in the reaction of alkylating agents with deoxyribosenucleic acid in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue distribution and mode of DNA methylation in mice by methyl methanesulphonate and N-methyl-N′-nitro-N-nitrosoguanidine: Lack of thymic lymphoma induction and low extent of methylation of target tissue DNA at O-6 of guanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms in alkylation mutagenesis. Induced reversion of bacteriophage T4rII AP72 by ethyl methanesulphonate in relation to extent and mode of ethylation of purines in bacteriophage deoxyribonucleic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction products from N-methyl-N-nitrosourea and deoxyribonucleic acid containing thymidine residues. Synthesis and identification of a new methylation product, O4-methylthymidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of DNA by 3H-14C-methyl-labelled N-methyl-N-nitrosourea--evidence for transfer of the intact methyl group.

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative Studies of the Hepatocarcinogen N,N-Dimethylnitrosamine in vivo: Reaction Sites in Rat Liver DNA and the Significance of their Relative Stabilities

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of ribonucleic acid by the carcinogens dimethyl sulphate, N-methyl-N-nitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine. Comparisons of chemical analyses at the nucleoside and base levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of Glutathione and Glutathione S-Transferases in Mercapturic Acid Biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction of diazoalkanes with 1-substituted 2, 4-dioxopyrimidines. Formation of O2, N-3 and O4-alkyl products

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kinetics of the alkaline hydrolysis of phosphotriesters in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exhaustion and recovery of repair excision of O6-methylguanine from rat liver DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of DNA in various organs of c57b1 mice by a carcinogenic dose of N-methyl-N-nitrosourea and stability of some methylation products up to 18 hours

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour induction by low molecular weight alkylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tables for use in fourfold contingency tests

1 reference

https://pubmed.ncbi.nlm.nih.gov/728073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ1741031

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:728073%20AND%20SRC:MED&resulttype=core&format=json

13 September 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:728073%20AND%20SRC:MED&resulttype=core&format=json

13 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:728073%20AND%20SRC:MED&resulttype=core&format=json

13 September 2019

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