Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin (Q62733752)

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27 October 2019

title

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin (English)

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27 October 2019

1

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27 October 2019

David M Sansom

5

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27 October 2019

author name string

Wilson A

2

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27 October 2019

Turner L

3

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27 October 2019

Westwick J

4

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27 October 2019

language of work or name

English

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publication date

1 February 1995

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European Journal of Immunology

27 October 2019

published in

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27 October 2019

volume

25

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issue

2

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page(s)

526-532

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Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

27 October 2019

cites work

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7 January 2021

The role of the CD28 receptor during T cell responses to antigen

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7 January 2021

The B7 and CD28 receptor families

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Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation

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7 January 2021

B70 antigen is a second ligand for CTLA-4 and CD28

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7 January 2021

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

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7 January 2021

B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.

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7 January 2021

Differential T cell costimulatory requirements in CD28-deficient mice

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7 January 2021

Ligation of CD28 receptor by B7 induces formation of D-3 phosphoinositides in T lymphocytes independently of T cell receptor/CD3 activation

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7 January 2021

Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

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Oncogenes and signal transduction

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

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7 January 2021

Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

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7 January 2021

SH2 domains recognize specific phosphopeptide sequences

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7 January 2021

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

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7 January 2021

Platelet-derived growth factor-induced phosphatidylinositol 3-kinase activation mediates actin rearrangements in fibroblasts

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7 January 2021

p21ras mediates control of IL-2 gene promoter function in T cell activation.

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7 January 2021

Regulation of D-3 phosphoinositides during T cell activation via the T cell antigen receptor/CD3 complex and CD2 antigens

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7 January 2021

Inhibition by staurosporine of mitogen-induced calcium mobilisation in human T lymphoblasts

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7 January 2021

The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase

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7 January 2021

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

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7 January 2021

Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells

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7 January 2021

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

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7 January 2021

CD28 of T lymphocytes associates with phosphatidylinositol 3-kinase

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7 January 2021

Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells

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7 January 2021

Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells

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7 January 2021

Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase

1 reference

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7 January 2021

The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes

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7 January 2021

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

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7 January 2021

Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85

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7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

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7 January 2021

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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7 January 2021

Identifiers

DOI

10.1002/EJI.1830250233

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7875215%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

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