Small-molecule-based strategies for controlling gene expression (Q74754870)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9653545%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

review article

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title

Small-molecule-based strategies for controlling gene expression (English)

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12 November 2019

author name string

C Denison

series ordinal

1

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12 November 2019

T Kodadek

series ordinal

2

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12 November 2019

publication date

1 June 1998

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12 November 2019

published in

Chemistry and Biology

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12 November 2019

volume

5

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12 November 2019

issue

6

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12 November 2019

page(s)

R129-45

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A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

12 November 2019

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The mechanism of action of cyclosporin A and FK506

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Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A

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Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity

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Three-part inventions: intracellular signaling and induced proximity

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Controlling Signal Transduction with Synthetic Ligands

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Dimeric ligands define a role for transcriptional activation domains in reinitiation

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The general transcription factors of RNA polymerase II

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General initiation factors for RNA polymerase II.

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Biochemistry and structural biology of transcription factor IID (TFIID)

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7 January 2021

Co-crystal structure of TBP recognizing the minor groove of a TATA element

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7 January 2021

Crystal structure of a yeast TBP/TATA-box complex

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7 January 2021

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

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7 January 2021

Evidence for functional binding and stable sliding of the TATA binding protein on nonspecific DNA

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7 January 2021

Direct recognition of initiator elements by a component of the transcription factor IID complex

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7 January 2021

Drosophila TAFII150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA.

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7 January 2021

Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II

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7 January 2021

The RNA polymerase II general elongation factors

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7 January 2021

Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

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7 January 2021

Five intermediate complexes in transcription initiation by RNA polymerase II

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7 January 2021

Crystal structure of the yeast TFIIA/TBP/DNA complex

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7 January 2021

The yeast TAF145 inhibitory domain and TFIIA competitively bind to TATA-binding protein

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7 January 2021

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.

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7 January 2021

An RNA polymerase II holoenzyme responsive to activators

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7 January 2021

Crystal structure of a TFIIB-TBP-TATA-element ternary complex

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7 January 2021

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7 January 2021

Mechanisms of transcriptional activation in vivo: two steps forward

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7 January 2021

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

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7 January 2021

Recycling of the general transcription factors during RNA polymerase II transcription

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7 January 2021

The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction

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7 January 2021

Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo

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7 January 2021

Increased recruitment of TATA-binding protein to the promoter by transcriptional activation domains in vivo

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7 January 2021

Contact with a component of the polymerase II holoenzyme suffices for gene activation

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7 January 2021

Gene activation by recruitment of the RNA polymerase II holoenzyme

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7 January 2021

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

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7 January 2021

Multiple TAFIIs directing synergistic activation of transcription

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7 January 2021

TBP-associated factors are not generally required for transcriptional activation in yeast

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7 January 2021

Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation

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7 January 2021

Transcription activation in cells lacking TAFIIS.

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7 January 2021

Yeast TAF(II)145 required for transcription of G1/S cyclin genes and regulated by the cellular growth state

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7 January 2021

The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II

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7 January 2021

Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription

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7 January 2021

RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster cells

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7 January 2021

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

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7 January 2021

Chromatin as an essential part of the transcriptional mechanim

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7 January 2021

Repression and activation by multiprotein complexes that alter chromatin structure

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7 January 2021

Eukaryotic transcription: an interlaced network of transcription factors and chromatin-modifying machines

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7 January 2021

Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation

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7 January 2021

Retinoblastoma protein recruits histone deacetylase to repress transcription

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7 January 2021

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

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7 January 2021

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

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7 January 2021

The yeast SWI-SNF complex facilitates binding of a transcriptional activator to nucleosomal sites in vivo

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7 January 2021

DNA-binding properties of the yeast SWI/SNF complex

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7 January 2021

Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex

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7 January 2021

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

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7 January 2021

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains

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7 January 2021

Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo.

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7 January 2021

The TAF(II)250 subunit of TFIID has histone acetyltransferase activity

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7 January 2021

RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling

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7 January 2021

Synergism in transcriptional activation: a kinetic view

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7 January 2021

The mechanism of transcriptional synergy of an in vitro assembled interferon-beta enhanceosome

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7 January 2021

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

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7 January 2021

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

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7 January 2021

Biochemical evidence that a D-loop is part of a four-stranded PNA-DNA bundle. Nickel-mediated cleavage of duplex DNA by a Gly-Gly-His bis-PNA

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7 January 2021

Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA.

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7 January 2021

Genetic engineering of proteins with cell membrane permeability

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7 January 2021

Recognition of DNA by designed ligands at subnanomolar concentrations

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7 January 2021

Design of a G.C-specific DNA minor groove-binding peptide.

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7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

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7 January 2021

Targeting the minor groove of DNA.

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7 January 2021

On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides

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7 January 2021

Regulation of gene expression by small molecules

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7 January 2021

Inhibition of major-groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg positive patch

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7 January 2021

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex

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7 January 2021

TFIID binds in the minor groove of the TATA box

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7 January 2021

Functional distinctions between yeast TATA elements

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7 January 2021

Strategies for the design of minor groove binders: a re-evaluation based on the emergence of site-selective carbohydrate binders

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7 January 2021

A novel genetic system to detect protein-protein interactions

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7 January 2021

Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein-protein interactions

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7 January 2021

The reverse two-hybrid system: a genetic scheme for selection against specific protein/protein interactions

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7 January 2021

Sequence requirements for coiled-coils: analysis with lambda repressor-GCN4 leucine zipper fusions

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7 January 2021

Small molecule-dependent genetic selection in stochastic nanodroplets as a means of detecting protein-ligand interactions on a large scale

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7 January 2021

A miniaturized arrayed assay format for detecting small molecule-protein interactions in cells

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7 January 2021

Tumour suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage.

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7 January 2021

The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

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7 January 2021

10.1016/S1074-5521(98)90167-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9653545%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

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