Amplification of GAA/TTC triplet repeat in vitro: preferential expansion of (TTC)n strand (Q74825113)

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13 November 2019

title

Amplification of GAA/TTC triplet repeat in vitro: preferential expansion of (TTC)n strand (English)

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13 November 2019

1

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13 November 2019

author name string

L W Chow

series ordinal

2

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13 November 2019

M Hsieh

series ordinal

3

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13 November 2019

language of work or name

English

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publication date

1 August 1998

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Biochimica et Biophysica Acta

13 November 2019

published in

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13 November 2019

volume

1407

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13 November 2019

issue

2

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13 November 2019

page(s)

155-162

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Fragile X genotype characterized by an unstable region of DNA.

13 November 2019

cites work

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Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

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Triplet Repeat Expansion Mutations: The Example of Fragile X Syndrome

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Unstable triplet repeat sequences: a source of cancer mutations?

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Molecular basis of genetic instability of triplet repeats

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Expanded glutamines and neurodegeneration--a gain of insight

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Molecular genetics of triplet repeats: unstable expansion of triplet repeats as a new mechanism for neurodegenerative diseases.

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Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

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The expanding world of trinucleotide repeats

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Characteristic enrichment of DNA repeats in different genomes

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A single trinucleotide, 5'AGC3'/5'GCT3', of the triplet-repeat disease genes confers metal ion-induced non-B DNA structure

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Flexible DNA: genetically unstable CTG.CAG and CGG.CCG from human hereditary neuromuscular disease genes.

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Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications

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Trinucleotide repeats that expand in human disease form hairpin structures in vitro

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Solution structures of the individual single strands of the fragile X DNA triplets (GCC)n.(GGC)n

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7 January 2021

The trinucleotide repeat sequence d(CGG)15 forms a heat-stable hairpin containing Gsyn. Ganti base pairs

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Hairpin properties of single-stranded DNA containing a GC-rich triplet repeat: (CTG)15.

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The trinucleotide repeat sequence d(GTC)15adopts ahairpin conformation

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The purine-rich trinucleotide repeat sequences d(CAG)15 and d(GAC)15 form hairpins

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7 January 2021

Stability of intrastrand hairpin structures formed by the CAG/CTG class of DNA triplet repeats associated with neurological diseases

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DNA CTG triplet repeats involved in dynamic mutations of neurologically related gene sequences form stable duplexes

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The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure

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7 January 2021

Solution structure of a DNA quadruplex containing the fragile X syndrome triplet repeat

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7 January 2021

In vitro expansion of GGC:GCC repeats: identification of the preferred strand of expansion.

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Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9685624%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

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