Pharmacogenetics and cancer chemotherapy (Q77809056)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9893619%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

review article

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title

Pharmacogenetics and cancer chemotherapy (English)

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8 December 2019

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2

M J Ratain

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8 December 2019

author name string

L Iyer

series ordinal

1

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8 December 2019

publication date

1 September 1998

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European Journal of Cancer

8 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9893619%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

volume

34

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8 December 2019

issue

10

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8 December 2019

page(s)

1493-1499

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Pharmacogenetics: its biologic roots and the medical challenge

8 December 2019

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Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism

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Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

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Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity

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7 January 2021

Clinical pharmacology of 5-fluorouracil

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Influence of sex and age on fluorouracil clearance

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7 January 2021

Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy

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7 January 2021

Dihydropyrimidine dehydrogenase activity in cancer patients

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7 January 2021

Population characteristics of hepatic dihydropyrimidine dehydrogenase activity, a key metabolic enzyme in 5-fluorouracil chemotherapy*

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7 January 2021

Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity

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7 January 2021

Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity

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7 January 2021

Correlation between catalytic activity and protein content for the polymorphically expressed dihydropyrimidine dehydrogenase in human lymphocytes.

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7 January 2021

Severe 5-fluorouracil toxicity in a patient with decreased dihydropyrimidine dehydrogenase activity

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7 January 2021

Population study of dihydropyrimidine dehydrogenase in cancer patients

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7 January 2021

Analysis of the dihydropyrimidine dehydrogenase polymorphism in a British population

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7 January 2021

cDNA cloning of bovine liver dihydropyrimidine dehydrogenase

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7 January 2021

Assignment of the human dihydropyrimidine dehydrogenase gene (DPYD) to chromosome region 1p22 by fluorescence in situ hybridization

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7 January 2021

Human polymorphism in drug metabolism: mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea.

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7 January 2021

A point mutation in an invariant splice donor site leads to exon skipping in two unrelated Dutch patients with dihydropyrimidine dehydrogenase deficiency

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Mutations at codon 974 of the DPYD gene are a rare event

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Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity

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7 January 2021

Glutathione transferases and cancer

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Simultaneous characterization of glutathione S-transferase M1 and T1 polymorphisms by polymerase chain reaction in American whites and blacks

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7 January 2021

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7 January 2021

Identification of human liver aldehyde dehydrogenases that catalyze the oxidation of aldophosphamide and retinaldehyde

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Determination of CYP2C19 phenotype in black Americans with omeprazole: correlation with genotype

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7 January 2021

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7 January 2021

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7 January 2021

Absence of CYP3A genetic polymorphism assessed by urinary excretion of 6 beta-hydroxycortisol in 102 healthy subjects on rifampicin

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7 January 2021

Identification of the major human hepatic cytochrome P450 involved in activation and N-dechloroethylation of ifosfamide

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7 January 2021

Human liver microsomal cytochrome P450 3A isozymes mediated vindesine biotransformation. Metabolic drug interactions

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7 January 2021

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

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7 January 2021

Identification of P450 enzymes involved in metabolism of verapamil in humans

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7 January 2021

Biochemical individuality: the next generation

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7 January 2021

Dose calculation of anticancer drugs: a review of the current practice and introduction of an alternative

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7 January 2021

Human DNA polymorphisms and methods of analysis

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7 January 2021

Genetic analysis using the polymerase chain reaction

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7 January 2021

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Identifiers

DOI

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8 December 2019

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