Rodent models for the study of type 2 diabetes in children (juvenile diabesity) (Q79767738)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15016157%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Rodent models for the study of type 2 diabetes in children (juvenile diabesity) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15016157%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

Clayton E Mathews

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15016157%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

publication date

1 September 2002

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15016157%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15016157%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15016157%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15016157%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

163-173

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15016157%20AND%20SRC:MED&resulttype=core&format=json

Non-insulin-dependent diabetes mellitus in childhood and adolescence

25 December 2019

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Type 2 diabetes mellitus in minority children and adolescents. An emerging problem

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21 January 2018

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Was there an epidemic of diabetes in nonwhite adolescents in Allegheny County, Pennsylvania?

21 January 2018

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Thinness at birth and insulin resistance in adult life.

21 January 2018

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Fetal growth and impaired glucose tolerance in men and women

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Type 2 diabetes mellitus in UK children--an emerging problem.

21 January 2018

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Early presentation of type 2 diabetes mellitus in young New Zealand Maori

21 January 2018

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Diabetic ketoacidosis among obese African-American adolescents with NIDDM.

21 January 2018

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Pathogenic factors of glucose intolerance in obese Japanese adolescents with type 2 diabetes

21 January 2018

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Type 2 diabetes mellitus in children and youth: a new epidemic

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Emerging epidemic of type 2 diabetes in youth

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Genetic models for non insulin dependent diabetes mellitus in rodents

21 January 2018

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Genetic models of obesity and energy balance in the mouse

21 January 2018

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A polymorphic marker in the leptin gene associated with Japanese morbid obesity

21 January 2018

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Transmission disequilibrium and sequence variants at the leptin receptor gene in extremely obese German children and adolescents

21 January 2018

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Obese, a new mutation in the house mouse

21 January 2018

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Positional cloning of the mouse obese gene and its human homologue

21 January 2018

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Leptin, leptin receptors, and the control of body weight.

21 January 2018

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Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

21 January 2018

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Impairment of Glucose Tolerance in Yellow (Avy/A)(BALB/c × VY) F-l Hybrid Mice by Hyperglycemic Peptide(s) from Human Pituitary Glands*

21 January 2018

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Insulin resistance in genetically obese, hyperglycemic mice.

21 January 2018

1 reference

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Laboratory animals exhibiting obesity and diabetes syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Hyperinsulinemia in pre-weaning diabetes (db) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Diabetes, a New Mutation in the Mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Studies in the diabetic mutant mouse. I. Light microscopy and radioautography of pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Hormone regulation of glucose metabolism in the genetically obese-diabetic mouse (db/db): glucose metabolism in the perfused hindquarters of lean and obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Glucose transporter levels in spontaneously obese (db/db) insulin-resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Impaired insulin receptor phosphorylation in skeletal muscle membranes of db/db mice: the use of a novel skeletal muscle plasma membrane preparation to compare insulin binding and stimulation of receptor phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Role of the agouti gene in obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Molecular characterization of the mouse agouti locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

A molecular model for the genetic and phenotypic characteristics of the mouse lethal yellow (Ay) mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Transcriptional regulation of the adipocyte fatty acid synthase gene by agouti: interaction with insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Regulation of leptin by agouti

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Inhibition of cyclic AMP accumulation by endothelin is pertussis toxin sensitive and calcium independent in isolated adult feline cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Agouti regulation of intracellular calcium: role in the insulin resistance of viable yellow mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Effects of ciglitazone on endogenous plasma islet amyloid polypeptide and insulin sensitivity in obese-diabetic viable yellow mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Pancreatic islet cells in preobese yellow Avy/- mice: relation to adult hyperinsulinemia and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Role of stress in the etiology and treatment of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Alprazolam reduces stress hyperglycemia in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Constitutive differences in antioxidant defense status distinguish alloxan-resistant and alloxan-susceptible mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Resistance of ALR/Lt islets to free radical-mediated diabetogenic stress is inherited as a dominant trait.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Genetic analysis of a new mouse model for non-insulin-dependent diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

A new mouse model of spontaneous diabetes derived from ddY strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Impairment of insulin-stimulated GLUT4 translocation in skeletal muscle and adipose tissue in the Tsumura Suzuki obese diabetic mouse: a new genetic animal model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Genetic analysis of obese diabetes in the TSOD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

NIDDM genes in mice: deleterious synergism by both parental genomes contributes to diabetogenic thresholds

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Obesity QTLs on mouse chromosomes 2 and 17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Regional fat distribution and metabolism in a new mouse model (C57BL/6J) of non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Defective glucose-stimulated insulin release from perifused islets of C57BL/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Impaired second phase insulin response of diabetes-prone C57BL/6J mouse islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Transient effects of long-term leptin supplementation in the prevention of diet-induced obesity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Hyperinsulinemia in the pregnant C57BL/6J mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

beta-cell function and viability in the spontaneously diabetic GK rat: information from the GK/Par colony

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Deficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Abnormal insulin secretion and glucose metabolism in pancreatic islets from the spontaneously diabetic GK rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Glucose sensitivity of ATP-sensitive K+ channels is impaired in beta-cells of the GK rat. A new genetic model of NIDDM

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Impact of diabetic inheritance on glucose tolerance and insulin secretion in spontaneously diabetic GK-Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Pathophysiological and genetic characterization of the major diabetes locus in GK rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db).

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Leptin receptor missense mutation in the fatty Zucker rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr).

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Constitutive and impaired signaling of leptin receptors containing the Gln --> Pro extracellular domain fatty mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Evolution of β-Cell Dysfunction in the Male Zucker Diabetic Fatty Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Basal insulin hypersecretion in insulin-resistant Zucker diabetic and Zucker fatty rats: role of enhanced fuel metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Evidence that down-regulation of beta-cell glucose transporters in non-insulin-dependent diabetes may be the cause of diabetic hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

In vivo prevention of hyperglycemia also prevents glucotoxic effects on PDX-1 and insulin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Caloric restriction in obese pre-diabetic rats prevents beta-cell depletion, loss of beta-cell GLUT 2 and glucose incompetence

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Induction of uncoupling protein-2 mRNA by troglitazone in the pancreatic islets of Zucker diabetic fatty rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonist, JTT-501, on diabetic complications in Zucker diabetic fatty rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

A genetic defect in beta-cell gene expression segregates independently from the fa locus in the ZDF rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Diabetes is associated with autoimmunity in the New Zealand obese (NZO) mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

A possible mechanism for insulin resistance and hyperglycaemia in NZO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

NIDDM-Y in First Nation children in Canada

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

High Prevalence of Diabetes in Young Pima Indians: Evidence of Phenotypic Variation in a Genetically Isolated Population

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Incidence of insulin-dependent diabetes (IDDM) and non-insulin-dependent diabetes (NIDDM) (0-34 years at onset) in Benghazi, Libya

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Increased incidence of non-insulin dependent diabetes mellitus among Japanese schoolchildren correlates with an increased intake of animal protein and fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Early presentation of type 2 diabetes in Mexican-American youth

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Increased incidence of non-insulin-dependent diabetes mellitus among adolescents

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

Type 2 diabetes mellitus in children: pathophysiology and risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

7 January 2021

Association of the G-2548A polymorphism in the 5′ region of the LEP gene with overweight

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

7 January 2021

The role of the agouti gene in the yellow obese syndrome

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

7 January 2021

Reduced sensitivity of dihydroxyacetone on ATP-sensitive K+ channels of pancreatic beta cells in GK rats

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

7 January 2021

The pathogenesis of NIDDM: the role of the pancreatic beta cell

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

7 January 2021

A point mutation in the mitochondrial DNA of diabetes-prone BHE/cdb rats

1 reference

https://api.crossref.org/works/10.1034%2FJ.1399-5448.2002.30307.X

7 January 2021

10.1034/J.1399-5448.2002.30307.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15016157%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference