Control of E2F activity by p21Waf1/Cip1 (Q73023858)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10498892%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

Control of E2F activity by p21Waf1/Cip1 (English)

1 reference

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31 October 2019

author name string

Delavaine L

series ordinal

1

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31 October 2019

La Thangue NB

series ordinal

2

1 reference

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31 October 2019

language of work or name

English

0 references

publication date

1 September 1999

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31 October 2019

1 reference

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31 October 2019

volume

18

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31 October 2019

issue

39

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31 October 2019

page(s)

5381-5392

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p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

31 October 2019

cites work

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7 January 2021

Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F.

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DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein

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Direct transcriptional repression by pRB and its reversal by specific cyclins

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Radiation-induced cell cycle arrest compromised by p21 deficiency

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

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Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control

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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein

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7 January 2021

Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition

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7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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7 January 2021

The regulation of E2F by pRB-family proteins

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

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7 January 2021

Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

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7 January 2021

Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes

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7 January 2021

Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA

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7 January 2021

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

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7 January 2021

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

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7 January 2021

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

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7 January 2021

The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.

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7 January 2021

p53: puzzle and paradigm

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Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

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7 January 2021

Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

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7 January 2021

New functional activities for the p21 family of CDK inhibitors

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7 January 2021

DP and E2F proteins: coordinating transcription with cell cycle progression.

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7 January 2021

Functional interplay between p53 and E2F through co-activator p300.

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7 January 2021

p53, the cellular gatekeeper for growth and division

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Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

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7 January 2021

Analysis of wild-type and mutant p21WAF-1 gene activities

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Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

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7 January 2021

The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

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7 January 2021

The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition

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7 January 2021

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

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7 January 2021

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

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7 January 2021

Ultraviolet Light Induces Expression of p53 and p21 in Human Skin: Effect of Sunscreen and Constitutive p21 Expression in Skin Appendages

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7 January 2021

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

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7 January 2021

Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site

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7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

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7 January 2021

A non-enzymatic p21 protein inhibitor of stress-activated protein kinases

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7 January 2021

Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair

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7 January 2021

A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter

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7 January 2021

Regulation of the cell cycle by viral oncoproteins

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7 January 2021

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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7 January 2021

The retinoblastoma protein and cell cycle control

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

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7 January 2021

Transcriptional repression by the Rb-related protein p107.

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7 January 2021