Concomitant use of cytochrome P450 3A4 inhibitors and simvastatin (Q73065060)

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31 October 2019

meta-analysis

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title

Concomitant use of cytochrome P450 3A4 inhibitors and simvastatin (English)

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31 October 2019

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P J Gruer

1

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31 October 2019

J M Vega

2

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31 October 2019

M F Mercuri

3

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M R Dobrinska

4

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31 October 2019

J A Tobert

5

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31 October 2019

language of work or name

English

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publication date

1 October 1999

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American Journal of Cardiology

31 October 2019

published in

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volume

84

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issue

7

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31 October 2019

page(s)

811-815

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In vitro and in vivo drug interactions involving human CYP3A.

31 October 2019

cites work

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Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations

7 January 2021

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The interaction of diltiazem with lovastatin and pravastatin

7 January 2021

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Safety and tolerability of cholesterol lowering with simvastatin during 5 years in the Scandinavian Simvastatin Survival Study

7 January 2021

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MRC/BHF Heart Protection Study of cholesterol-lowering therapy and of antioxidant vitamin supplementation in a wide range of patients at increased risk of coronary heart disease death: early safety and efficacy experience

7 January 2021

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Comparative pharmacokinetics of lovastatin, simvastatin and pravastatin in humans

7 January 2021

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Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar?

7 January 2021

1 reference

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Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

7 January 2021

1 reference

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Biotransformation of lovastatin. IV. Identification of cytochrome P450 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes

7 January 2021

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Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses

7 January 2021

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Low-dose simvastatin for the treatment of hypercholesterolaemia in recipients of cardiac transplantation

7 January 2021

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10.1016/S0002-9149(99)00442-7

7 January 2021

Identifiers

DOI

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31 October 2019

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