Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine (Q73423116)

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3 November 2019

title

Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine (English)

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3 November 2019

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2

O A Olivero

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3 November 2019

author name string

R P Agarwal

series ordinal

1

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3 November 2019

language of work or name

English

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publication date

1 May 1997

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3 November 2019

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3 November 2019

volume

390

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3 November 2019

issue

3

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3 November 2019

page(s)

223-231

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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

3 November 2019

cites work

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Biochemical pharmacology of zidovudine in human T-lymphoblastoid cells (CEM).

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Preferential incorporation of 3'-azido-2',3'-dideoxythymidine into telomeric DNA and Z-DNA-containing regions of Chinese hamster ovary cells

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Thymidine and zidovudine metabolism in chronically zidovudine-exposed cells in vitro

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7 January 2021

Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosides

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Effect of anti-HIV 2'-beta-fluoro-2',3'-dideoxynucleoside analogs on the cellular content of mitochondrial DNA and on lactate production.

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The pc12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs

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Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis

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Mitochondrial myopathy caused by long-term zidovudine therapy

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Zidovudine myopathy: a distinctive disorder associated with mitochondrial dysfunction

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Telomeres, telomerase and senescence

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Zidovudine-induced mitochondrial myopathy is associated with muscle carnitine deficiency and lipid storage

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7 January 2021

Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases

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Functional Evidence for an RNA Template in Telomerase

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Induction of micronuclei in mouse bone marrow cells: an evaluation of nucleoside analogues used in the treatment of AIDS.

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Genotoxic activity of azidothymidine (AZT) in in vitro systems

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Ultrastructural characteristics and DNA immunocytochemistry in human immunodeficiency virus and zidovudine-associated myopathies

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The cytogenetic effects of AZT

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7 January 2021

10.1016/S1383-5718(97)00014-4

Identifiers

DOI

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3 November 2019

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